Gene regulation is a ubiquitous mechanism by which organisms respond to their
environment. While organisms are often found to be adapted to the environments they …

A central goal of evolutionary genetics is to understand, at the molecular level, how
organisms adapt to their environments. For a given trait, the answer often involves the …

Understanding complex genotype-by-environment interactions (GEIs) is crucial for
understanding phenotypic variation. An important factor often overlooked in GEI studies is …

One of the most important aspects of the evolution of development and physiology is the
interplay between gene expression and the environment, by which traits become altered in …

While the underlying genetic changes have been uncovered in some cases of adaptive
evolution, the lack of a systematic study prevents a general understanding of the genomic …

Despite the greater functional importance of protein levels, our knowledge of gene
expression evolution is based almost entirely on studies of mRNA levels. In contrast, our …

Noncoding genetic variation is known to significantly influence gene expression levels in a
growing number of specific cases; however, the patterns of genome-wide noncoding …

Many familiar traits in the natural world—from lions' manes to the longevity of bristlecone
pine trees—arose in the distant past, and have long since fixed in their respective species. A …

Heritable changes in gene expression are important contributors to phenotypic differences
within and between species and are caused by mutations in cis-regulatory elements and …

Background Comparative genomics brings insight into sequence evolution, but even more
may be learned by coupling sequence analyses with experimental tests of gene function …