Cis-Regulatory Divergence in Gene Expression between Two Thermally Divergent Yeast Species
Gene regulation is a ubiquitous mechanism by which organisms respond to their
environment. While organisms are often found to be adapted to the environments they …
environment. While organisms are often found to be adapted to the environments they …
Joint effects of genes underlying a temperature specialization tradeoff in yeast
F AlZaben, JN Chuong, MB Abrams, RB Brem - PLoS Genetics, 2021 - journals.plos.org
A central goal of evolutionary genetics is to understand, at the molecular level, how
organisms adapt to their environments. For a given trait, the answer often involves the …
organisms adapt to their environments. For a given trait, the answer often involves the …
Transient genotype-by-environment interactions following environmental shock provide a source of expression variation for essential genes
Understanding complex genotype-by-environment interactions (GEIs) is crucial for
understanding phenotypic variation. An important factor often overlooked in GEI studies is …
understanding phenotypic variation. An important factor often overlooked in GEI studies is …
Genome-wide scan reveals that genetic variation for transcriptional plasticity in yeast is biased towards multi-copy and dispensable genes
One of the most important aspects of the evolution of development and physiology is the
interplay between gene expression and the environment, by which traits become altered in …
interplay between gene expression and the environment, by which traits become altered in …
The loci of environmental adaptation in a model eukaryote
While the underlying genetic changes have been uncovered in some cases of adaptive
evolution, the lack of a systematic study prevents a general understanding of the genomic …
evolution, the lack of a systematic study prevents a general understanding of the genomic …
Evolution at two levels of gene expression in yeast
CG Artieri, HB Fraser - Genome research, 2014 - genome.cshlp.org
Despite the greater functional importance of protein levels, our knowledge of gene
expression evolution is based almost entirely on studies of mRNA levels. In contrast, our …
expression evolution is based almost entirely on studies of mRNA levels. In contrast, our …
Population Genomics and Transcriptional Consequences of Regulatory Motif Variation in Globally Diverse Saccharomyces cerevisiae Strains
Noncoding genetic variation is known to significantly influence gene expression levels in a
growing number of specific cases; however, the patterns of genome-wide noncoding …
growing number of specific cases; however, the patterns of genome-wide noncoding …
Population and comparative genetics of thermotolerance divergence between yeast species
MB Abrams, CA Dubin, F AlZaben, J Bravo, PM Joubert… - G3, 2021 - academic.oup.com
Many familiar traits in the natural world—from lions' manes to the longevity of bristlecone
pine trees—arose in the distant past, and have long since fixed in their respective species. A …
pine trees—arose in the distant past, and have long since fixed in their respective species. A …
[PDF][PDF] Evolutionary dynamics of regulatory changes underlying gene expression divergence among Saccharomyces species
BPH Metzger, PJ Wittkopp… - Genome Biology and …, 2017 - academic.oup.com
Heritable changes in gene expression are important contributors to phenotypic differences
within and between species and are caused by mutations in cis-regulatory elements and …
within and between species and are caused by mutations in cis-regulatory elements and …
Comparative gene expression between two yeast species
Background Comparative genomics brings insight into sequence evolution, but even more
may be learned by coupling sequence analyses with experimental tests of gene function …
may be learned by coupling sequence analyses with experimental tests of gene function …