Two decades of new drug discovery and development for Alzheimer's disease

Z Liu, A Zhang, H Sun, Y Han, L Kong, X Wang - RSC advances, 2017 - pubs.rsc.org
Alzheimer's disease is a progressive and irreversible neurodegenerative disease,
associated with a decreased cognitive function and severe behavioral abnormalities. Due to …

Therapeutic approach to Alzheimer's disease: Current treatments and new perspectives

T Pardo-Moreno, A González-Acedo… - Pharmaceutics, 2022 - mdpi.com
Alzheimer's disease (AD) is the most common cause of dementia. The pathophysiology of
this disease is characterized by the accumulation of amyloid-β, leading to the formation of …

Advances in drug therapy for Alzheimer's disease

C Zhu, S Fu, Y Chen, L Li, R Mao, J Wang, R Liu… - Current medical …, 2020 - Springer
Alzheimer's disease (AD) is a chronic neurodegenerative disease that mainly causes
dementia. It is a serious threat to the health of the global elderly population. Considerable …

Treatment of Alzheimer's disease: beyond symptomatic therapies

FR Buccellato, M D'Anca, GM Tartaglia… - International Journal of …, 2023 - mdpi.com
In an ever-increasing aged world, Alzheimer's disease (AD) represents the first cause of
dementia and one of the first chronic diseases in elderly people. With 55 million people …

Neurodegenerative pathways in Alzheimer's disease: a review

AK Ramachandran, S Das, A Joseph… - Current …, 2021 - ingentaconnect.com
Alzheimer's disease (AD) is a complex neurodegenerative disease that leads to insidious
deterioration of brain functions and is considered the sixth leading cause of death in the …

Alzheimer's disease: a systemic review of substantial therapeutic targets and the leading multi-functional molecules

T Umar, N Hoda - Current Topics in Medicinal Chemistry, 2017 - ingentaconnect.com
Alzheimer's Disease (AD) is a fatal neurodegenerative disorder, having a complex aetiology
with numerous possible drug targets. There are targets that have been known for years …

Recent advances on drug development and emerging therapeutic agents for Alzheimer's disease

T Athar, K Al Balushi, SA Khan - Molecular biology reports, 2021 - Springer
Alzheimer's disease (AD) is a neurodegenerative old age disease that is complex,
multifactorial, unalterable, and progressive in nature. The currently approved therapy …

Current status of drug targets and emerging therapeutic strategies in the management of Alzheimer's disease

S Ghosh, S Durgvanshi, S Agarwal… - Current …, 2020 - ingentaconnect.com
Alzheimer's disease (AD) is a chronic neurodegenerative disease affecting the elderly. AD is
associated with a progressive decline in memory and cognitive abilities, drastic changes in …

[PDF][PDF] Current therapeutic strategy in Alzheimer's disease

S Singh, AS Kushwah, R Singh… - Eur Rev Med …, 2012 - europeanreview.org
Alzheimer's disease (AD) is a chronic, progressive, neurodegenerative disorder that places
a substantial burden on patients, their families, and society. Alzheimer's disease (AD) is the …

Therapeutic approaches for the treatment of Alzheimer's disease: an overview

LF Lau, MA Brodney - Alzheimer's Disease, 2008 - Springer
Alzheimer's disease (AD) is a neurodegenerative disease that robs the minds of our elderly
population. Approximately one in every eight adults over the age of 65 and nearly half of …