Background Sarcoidosis is a multisystem granulomatous disease of unknown origin with a
variable and often unpredictable course and pattern of organ involvement. In this study we …

Sarcoidosis, a systemic granulomatous syndrome invariably affecting the lung, typically
spontaneously remits but in∼ 20% of cases progresses with severe lung dysfunction or …

Background Sarcoidosis is a multisystem immuno-inflammatory disorder of unknown
etiology that most commonly involves the lungs. We hypothesized that an unbiased …

Rationale Despite the availability of multi-“omics” strategies, insights into the etiology and
pathogenesis of sarcoidosis have been elusive. This is partly due to the lack of reliable …

Previously, we demonstrated concordance in differentially expressed genes in sarcoidosis
blood and lung, implicating shared dysfunction of specific immune pathways. In the present …

Pulmonary involvement occurs in up to 95% of sarcoidosis cases. In this pilot study, we
examine lung compartment-specific protein expression to identify pathways linked to …

Background Sarcoidosis is a granulomatous systemic disease of unknown etiology.
Mononuclear cells such as macrophages or lymphocytes in lung tissue and hilar or …

Transcriptome profiles in sarcoidosis and their potential ro... : Current Opinion in Pulmonary
Medicine Transcriptome profiles in sarcoidosis and their potential role in disease prediction …

Sarcoidosis is a systemic disease characterized by noncaseating granulomatous
inflammation with tremendous clinical heterogeneity and uncertain pathobiology and lacking …

Sarcoidosis is a systemic heterogeneous inflammatory disease characterized by the
presence of noncaseating epithelioid granulomas in one or multiple organs, with the lung …