Background Organocatalytic asymmetric Michael addition is a strong approach for CC bond
formation. The objective of the study is to design molecules by exploiting the efficiency of …

Chiral pyrrolidinyl-oxazole-carboxamides were synthesized and used as efficient new
organocatalysts for the asymmetric Michael addition of ketones with nitroalkenes under …

New l-proline-derived bifunctional secondary amine organocatalysts were synthesized for
enantioselective Michael reactions in water as a solvent. Application of these catalysts in …

Though many chiral amines such as l-proline and its derivatives have proven to be versatile
catalysts in many reactions, l-prolinol was seldom used as organocatalyst for reactions …

Ever since the discovery of enantioselective organocatalytic Michael addition reactions, it
has emerged as a significant path for synthesizing a variety of stereochemical products …

A simple and convenient strategy was developed to synthesize a new class of pyrrolidinyl–
camphor based bifunctional organocatalysts possessing varying functional linkers. Catalytic …

The formation of CC and CX bonds is a fundamental process in synthesis. In recent years
organocatalysis has become a powerful tool to achieve these steps in a highly …

The Michael addition reaction is one of the most classical reactions in organic synthesis as it
is widely applied to synthesis of CX (XC,= O, N, S) bonds to produce natural compounds …

Maleimides are often used as electrophiles in conventional reactions; however, their
application as nucleophiles is limited to only a few reactions, and reactions utilizing α …

Chiral (S)‐pyrrolidine trifluoromethanesulfonamide has been shown to serve as an effective
catalyst for direct Michael addition reactions of aldehydes and ketones with nitroolefins. A …