Secondary brain injury after intracerebral hemorrhage (ICH) is the main cause of poor
prognosis in ICH patients, but the underlying mechanisms remain less known. The …

Background Brain injury after intracerebral hemorrhage is extremely complicated, and the
exact mechanism remains puzzling. Piezo1, a novel mammalian mechanosensitive ion …

In intracerebral hemorrhage (ICH), the mechanical brain injury is a considerable and
indispensable factor determining the neurological functions and poor outcomes. Previous …

Piezo1 is a mechanically-gated calcium channel. Recent studies have shown that Piezo1, a
mechanically-gated calcium channel, can attenuate both psychosine-and …

Traumatic brain injury (TBI) can lead to short-term and long-term physical and cognitive
impairments, which have significant impacts on patients, families, and society. Currently …

Stroke is associated with high mortality and extremely high disability rate. Regulating
ferroptosis seems to be a promising way to treat ischemic stroke. After stroke, vasogenic …

Chronic cerebral hypoperfusion (CCH) plays a critical role in the onset and progression of
vascular dementia (VD), which is now recognized as the second most common form of …

Piezo1 mechanosensitive ion channel (MSC) plays a significant role in human physiology.
Despite several research on the function and expression of Piezo1 in the nervous system, its …

Abstract Objective We investigated whether Piezo1 could regulate oxygen-glucose
deprivation/reoxygenation injury of neurons through Ca 2+/calpain signaling. Methods …

Astrocytes are important for information processing in the brain and they achieve this by fine‐
tuning neuronal communication via continuous uptake and release of biochemical …