The immunology of long COVID
DM Altmann, EM Whettlock, S Liu… - Nature Reviews …, 2023 - nature.com
Long COVID is the patient-coined term for the disease entity whereby persistent symptoms
ensue in a significant proportion of those who have had COVID-19, whether asymptomatic …
ensue in a significant proportion of those who have had COVID-19, whether asymptomatic …
[HTML][HTML] COVID-19 immunobiology: lessons learned, new questions arise
A Kaklamanos, K Belogiannis, P Skendros… - Frontiers in …, 2021 - frontiersin.org
There is strong evidence that COVID-19 pathophysiology is mainly driven by a
spatiotemporal immune deregulation. Both its phenotypic heterogeneity, spanning from …
spatiotemporal immune deregulation. Both its phenotypic heterogeneity, spanning from …
Long COVID or post-COVID-19 syndrome: putative pathophysiology, risk factors, and treatments
SJ Yong - Infectious diseases, 2021 - Taylor & Francis
Long COVID or post-COVID-19 syndrome first gained widespread recognition among social
support groups and later in scientific and medical communities. This illness is poorly …
support groups and later in scientific and medical communities. This illness is poorly …
[HTML][HTML] Humoral immunity against SARS-CoV-2 and the impact on COVID-19 pathogenesis
E Lee, JE Oh - Molecules and cells, 2021 - Elsevier
It has been more than a year since severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) first emerged. Many studies have provided insights into the various aspects of the …
CoV-2) first emerged. Many studies have provided insights into the various aspects of the …
Unraveling the mystery surrounding post-acute sequelae of COVID-19
RK Ramakrishnan, T Kashour, Q Hamid… - Frontiers in …, 2021 - frontiersin.org
More than one year since its emergence, corona virus disease 2019 (COVID-19) is still
looming large with a paucity of treatment options. To add to this burden, a sizeable subset of …
looming large with a paucity of treatment options. To add to this burden, a sizeable subset of …
[PDF][PDF] Clinically identifiable autoreactivity is common in severe SARS-CoV-2 infection
Severe SARS-CoV-2 infection is linked to the presence of autoantibodies against multiple
targets, including phospholipids and type-I interferons. We recently identified activation of an …
targets, including phospholipids and type-I interferons. We recently identified activation of an …
Divergent adaptive immune responses define two types of long COVID
J Kervevan, I Staropoli, D Slama… - Frontiers in …, 2023 - frontiersin.org
Background The role of adaptive immune responses in long COVID remains poorly
understood, with contrasting hypotheses suggesting either an insufficient antiviral response …
understood, with contrasting hypotheses suggesting either an insufficient antiviral response …
Pathological sequelae of long-haul COVID
S Mehandru, M Merad - Nature immunology, 2022 - nature.com
The world continues to contend with successive waves of coronavirus disease 2019 (COVID-
19), fueled by the emergence of viral variants. At the same time, persistent, prolonged and …
19), fueled by the emergence of viral variants. At the same time, persistent, prolonged and …
[HTML][HTML] Long COVID: An inevitable sequela of SARS-CoV-2 infection
At present, there are more than 560 million confirmed cases of the coronavirus disease 2019
(COVID-19) worldwide. Although more than 98% of patients with severe acute respiratory …
(COVID-19) worldwide. Although more than 98% of patients with severe acute respiratory …
Immunological profiling in long COVID: overall low grade inflammation and T-lymphocyte senescence and increased monocyte activation correlating with increasing …
JC Berentschot, HA Drexhage… - Frontiers in …, 2023 - frontiersin.org
Background Many patients with SARS-CoV-2 infection develop long COVID with fatigue as
one of the most disabling symptoms. We performed clinical and immune profiling of fatigued …
one of the most disabling symptoms. We performed clinical and immune profiling of fatigued …