[HTML][HTML] Psilocybin-induced default mode network hypoconnectivity is blunted in alcohol-dependent rats
JR Reinwald, CN Schmitz, I Skorodumov… - Translational …, 2023 - nature.com
Abstract Alcohol Use Disorder (AUD) adversely affects the lives of millions of people, but still
lacks effective treatment options. Recent advancements in psychedelic research suggest …
lacks effective treatment options. Recent advancements in psychedelic research suggest …
[HTML][HTML] Psilocybin exerts distinct effects on resting state networks associated with serotonin and dopamine in mice
J Grandjean, D Buehlmann, M Buerge, H Sigrist… - Neuroimage, 2021 - Elsevier
Hallucinogenic agents have been proposed as potent antidepressants; this includes the
serotonin (5-HT) receptor 2A agonist psilocybin. In human subjects, psilocybin alters …
serotonin (5-HT) receptor 2A agonist psilocybin. In human subjects, psilocybin alters …
Effective connectivity of emotion and cognition under psilocybin
Classic psychedelics alter sense of self and patterns of self-related thought. These changes
are hypothesised to underlie their therapeutic efficacy across internalising pathologies such …
are hypothesised to underlie their therapeutic efficacy across internalising pathologies such …
Psilocybin induces time-dependent changes in global functional connectivity
Background The use of psilocybin in scientific and experimental clinical contexts has
triggered renewed interest in the mechanism of action of psychedelics. However, its time …
triggered renewed interest in the mechanism of action of psychedelics. However, its time …
[HTML][HTML] Psilocybin-induced changes in neural reactivity to alcohol and emotional cues in patients with alcohol use disorder: an fMRI pilot study
This pilot study investigated psilocybin-induced changes in neural reactivity to alcohol and
emotional cues in patients with alcohol use disorder (AUD). Participants were recruited from …
emotional cues in patients with alcohol use disorder (AUD). Participants were recruited from …
Psilocybin modulation of dynamic functional connectivity is associated with plasma psilocin and subjective effects
Background Psilocin, the neuroactive metabolite of psilocybin, is a serotonergic psychedelic
that induces an acute altered state of consciousness, evokes lasting changes in mood and …
that induces an acute altered state of consciousness, evokes lasting changes in mood and …
[HTML][HTML] Neural mechanisms of resting-state networks and the amygdala underlying the cognitive and emotional effects of psilocybin
Background Serotonergic psychedelics, such as psilocybin, alter perceptual and cognitive
systems that are functionally integrated with the amygdala. These changes can alter …
systems that are functionally integrated with the amygdala. These changes can alter …
[HTML][HTML] Psilocybin-induced changes in brain network integrity and segregation correlate with plasma psilocin level and psychedelic experience
MK Madsen, DS Stenbæk, A Arvidsson… - European …, 2021 - Elsevier
The emerging novel therapeutic psilocybin produces psychedelic effects via engagement of
cerebral serotonergic targets by psilocin (active metabolite). The serotonin 2A receptor …
cerebral serotonergic targets by psilocin (active metabolite). The serotonin 2A receptor …
[HTML][HTML] Psilocybin modulation of time-varying functional connectivity is associated with plasma psilocin and subjective effects
Background Psilocin, the neuroactive metabolite of psilocybin, is a serotonergic psychedelic
that induces an acute altered state of consciousness, evokes lasting changes in mood and …
that induces an acute altered state of consciousness, evokes lasting changes in mood and …
Acute Effects of Hallucinogens on Functional Connectivity: Psilocybin and Salvinorin-A
The extent of changes in functional connectivity (FC) within functional networks as a
common feature across hallucinogenic drug classes is under-explored. This work utilized …
common feature across hallucinogenic drug classes is under-explored. This work utilized …