IL-17 cytokines are expressed by numerous cells (eg, gamma delta (γδ) T, innate lymphoid
(ILC), Th17, epithelial cells). They contribute to the elimination of bacteria through the …

During T-cell receptor activation in a particular cytokine environment, naive CD4+ T cells
may differentiate into lineages defined by their pattern of cytokine production and …

The IL-17 family of cytokines has emerged over the last two decades as a pleiotropic group
of molecules that function in a wide variety of both beneficial and detrimental (pathological) …

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease that
causes high rates of disability and mortality worldwide because of severe progressive and …

The significance of Th17 cells and interleukin‐(IL‐) 17A signaling in host defense and
disease development has been demonstrated in various infection and autoimmune models …

Interleukin 17 (IL-17) is a key proinflammatory cytokine in the T helper 17 pathway. While it
is important in the clearance of certain pathogens, IL-17 has been shown to contribute to the …

Th17 cells are a proinflammatory subset of effector T cells that have been implicated in the
pathogenesis of asthma. Their production of the cytokine IL-17 is known to induce local …

The Th17 pathway has recently been shown to play a critical role in host defense, allergic
responses and autoimmune inflammation. Th17 cells predominantly produce IL-17 and IL …

T helper 17 (Th17) cytokines are now widely believed to be critical for the regulation of
various chronic immune diseases. Investigations have revealed a significant role for IL-17 …

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease of the
airways caused mainly by cigarette smoke exposure. COPD progression is marked by …