More than 100 single gene mutations and copy number variants convey risk for autism
spectrum disorder. To understand the extent to which each mutation contributes to the …

More than a hundred de novo single gene mutations and copy‐number variants have been
implicated in autism, each occurring in a small subset of cases. Mutant mouse models with …

Animal models provide preclinical tools to investigate the causal role of genetic mutations
and environmental factors in the etiology of autism spectrum disorder (ASD). Knockout and …

Autism is a heterogeneous neurodevelopmental disorder of unknown aetiology that affects 1
in 100–150 individuals. Diagnosis is based on three categories of behavioural criteria …

Autism is a neurodevelopmental disorder whose diagnosis is based on three behavioral
criteria: unusual reciprocal social interactions, deficits in communication, and stereotyped …

Autism is a neurodevelopmental syndrome with markedly high heritability. The diagnostic
indicators of autism are core behavioral symptoms, rather than definitive neuropathological …

Autism spectrum disorders (ASDs) present unique challenges in the fields of genetics and
neurobiology because of the clinical and molecular heterogeneity underlying these …

Understanding the neurobiological processes by which genotypes become phenotypes,
along with the advances in developmental neuroscience and neuronal networks at the …

Autism is a severe neurodevelopmental disorder, which typically emerges early in
childhood. The core symptoms of autism include deficits in social interaction, impaired …

Autism is a neurodevelopmental disorder that is currently diagnosed by the presence of
three behavioral criteria (1) qualitative impairments in reciprocal social interactions,(2) …