As chemically specialized forms of the extracellular matrix in the central nervous system,
polyanionic perineuronal nets (PNs) contain diverse constituents, including chondroitin …

Aggrecan, a chondroitin sulfate (CS) proteoglycan, forms lattice-like extracellular matrix
structures called perineuronal nets (PNNs). Neocortical PNNs primarily ensheath …

Perineuronal nets (PNNs) are aggregations of extracellular matrix molecules that are critical
for plasticity. Their altered development or changes during adulthood appear to contribute to …

Perineuronal nets represent highly specialized glial and glia-associated structures. In this
study, a triple fluorescence labeling of chondroitin sulfate proteoglycan-immunoreactive …

Previous lectin-histochemical and immunocytochemical investigations using fixed tissue
revealed perineuronal nets as lattice-like accumulations of extracellular matrix …

Background Proteoglycan (PG) in the extracellular matrix (ECM) of the central nervous
system (CNS) may act as a barrier for neurite elongation in a growth tract, and regulate other …

Perineuronal nets (PNs) consisting of polyanionic chondroitin sulfate proteoglycans (CSPG)
and other extracellular matrix components create an exceptional microenvironment around …

A special feature of the extracellular matrix in adult brains of various species is the
concentration of certain components around different sub-populations of neurones, giving …

Perineuronal net (PNN) is a highly structured portion of the CNS extracellular matrix (ECM)
regulating synaptic plasticity and a range of pathologic conditions including posttraumatic …

We developed a method to extract differentially chondroitin sulfate proteoglycans (CSPGs)
that are diffusely present in the central nervous system (CNS) matrix and CSPGs that are …