Acute kidney injury: what part do toll-like receptors play?

PG Vallés, AG Lorenzo, V Bocanegra… - International journal of …, 2014 - Taylor & Francis
The innate immune system plays an important role as a first response to tissue injury. This
first response is carried out via germline-encoded receptors. Toll-like receptors (TLRs) are …

Multifaceted roles of Toll-like receptors in acute kidney injury

R Habib - Heliyon, 2021 - cell.com
Toll-like receptors (TLRs) are a family of pattern recognition receptors (PRRs) in the first line
defense system of our bodies; they are widely expressed on leukocytes and kidney …

Toll-like receptors and their role in renal pathologies

T Eleftheriadis, G Pissas, V Liakopoulos… - … & Allergy-Drug …, 2012 - ingentaconnect.com
Toll-like receptors (TLRs) are the first identified and best studied family of pattern recognition
receptors. Expressed in immunocytes, TLRs initiate innate immune responses and …

Toll-like receptor 4 in acute kidney injury

PG Vallés, AF Gil Lorenzo, RD Garcia… - International Journal of …, 2023 - mdpi.com
Acute kidney injury (AKI) is a common and devastating pathologic condition, associated with
considerable high morbidity and mortality. Although significant breakthroughs have been …

The role of Toll-like receptors in renal diseases

A Gluba, M Banach, S Hannam… - Nature Reviews …, 2010 - nature.com
Toll-like receptors (TLRs) have a key role in innate immunity. These receptors recognize
both pathogen-associated molecular patterns and molecules that are released from …

Tracking the toll of kidney disease

AC Shirali, DR Goldstein - Journal of the American Society of …, 2008 - journals.lww.com
Since the discovery of the Toll-like receptors and their crucial role as modulators of innate
immunity, there has been increasing appreciation of their role in human health and disease …

Toll-like receptors in kidney disease

KD Smith - Current opinion in nephrology and hypertension, 2009 - journals.lww.com
Toll-like receptors in kidney disease : Current Opinion in Nephrology and Hypertension Toll-like
receptors in kidney disease : Current Opinion in Nephrology and Hypertension Log in or …

Signaling danger: toll-like receptors and their potential roles in kidney disease

HJ Anders, B Banas, D Schlöndorff - Journal of the American …, 2004 - journals.lww.com
Toll-like receptors (TLR) are an emerging family of receptors that recognize pathogen-
associated molecular patterns and promote the activation of leukocytes and intrinsic renal …

Toll-like receptor 4: An attractive therapeutic target for acute kidney injury

AK Jha, S Gairola, S Kundu, P Doye, AM Syed, C Ram… - Life Sciences, 2021 - Elsevier
Acute kidney injury (AKI) is a progressive renal complication which significantly affects the
patient's life with huge economic burden. Untreated acute kidney injury eventually …

[HTML][HTML] Toll-like receptor 4 regulates early endothelial activation during ischemic acute kidney injury

J Chen, R John, JA Richardson, JM Shelton, XJ Zhou… - Kidney international, 2011 - Elsevier
Ischemic acute kidney injury (AKI) triggers an inflammatory response which exacerbates
injury that requires increased expression of endothelial adhesion molecules. To study this …