[HTML][HTML] Attenuation of cigarette-smoke-induced oxidative stress, senescence, and inflammation by berberine-loaded liquid crystalline nanoparticles: in vitro study in …

KR Paudel, N Panth, B Manandhar, SK Singh, G Gupta… - Antioxidants, 2022 - mdpi.com
Cigarette smoke is considered a primary risk factor for chronic obstructive pulmonary
disease. Numerous toxicants present in cigarette smoke are known to induce oxidative …

[HTML][HTML] Zerumbone liquid crystalline nanoparticles protect against oxidative stress, inflammation and senescence induced by cigarette smoke extract in vitro

KR Paudel, DD Clarence, N Panth… - Naunyn-schmiedeberg's …, 2024 - Springer
The purpose of this study was to evaluate the potential of zerumbone-loaded liquid
crystalline nanoparticles (ZER-LCNs) in the protection of broncho-epithelial cells and …

Rutin-loaded liquid crystalline nanoparticles attenuate oxidative stress in bronchial epithelial cells: a PCR validation

M Mehta, KR Paudel, SD Shukla… - Future medicinal …, 2021 - Future Science
Aim: In the present study, the inhibitory potential of rutin-loaded liquid crystalline
nanoparticles (LCNs) on oxidative stress was determined in human bronchial epithelial cells …

Berberine loaded liquid crystalline nanostructure inhibits cancer progression in adenocarcinomic human alveolar basal epithelial cells in vitro

M Mehta, V Malyla, KR Paudel… - Journal of food …, 2021 - Wiley Online Library
Metastasis represents the leading cause of death in lung cancer patients. C‐X‐C Motif
Chemokine Ligand 8 (CXCL‐8), Chemokine (C‐C motif) ligand 20 (CCL‐20) and heme …

Rutin loaded liquid crystalline nanoparticles inhibit lipopolysaccharide induced oxidative stress and apoptosis in bronchial epithelial cells in vitro

KR Paudel, R Wadhwa, M Mehta, DK Chellappan… - Toxicology in vitro, 2020 - Elsevier
Airway inflammation and infections are the primary causes of damage in the airway
epithelium, that lead to hypersecretion of mucus and airway hyper-responsiveness. The role …

[HTML][HTML] Agarwood oil nanoemulsion attenuates cigarette smoke-induced inflammation and oxidative stress markers in BCi-NS1. 1 airway epithelial cells

G De Rubis, KR Paudel, B Manandhar, SK Singh… - Nutrients, 2023 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is an irreversible inflammatory respiratory
disease characterized by frequent exacerbations and symptoms such as cough and …

[HTML][HTML] Phytantriol-based berberine-loaded liquid crystalline nanoparticles attenuate inflammation and oxidative stress in lipopolysaccharide-induced RAW264. 7 …

AM Alnuqaydan, AG Almutary, M Azam, B Manandhar… - Nanomaterials, 2022 - mdpi.com
Inflammation and oxidative stress are interrelated processes that represent the underlying
causes of several chronic inflammatory diseases that include asthma, cystic fibrosis, chronic …

[HTML][HTML] Berberine-loaded liquid crystalline nanoparticles inhibit non-small cell lung cancer proliferation and migration in vitro

KR Paudel, M Mehta, GHS Yin, LL Yen… - … Science and Pollution …, 2022 - Springer
Non-small cell lung cancer (NSCLC) is reported to have a high incidence rate and is one of
the most prevalent types of cancer contributing towards 85% of all incidences of lung cancer …

Berberine-loaded engineered nanoparticles attenuate TGF-β-induced remodelling in human bronchial epithelial cells

G De Rubis, KR Paudel, G Liu, V Agarwal… - Toxicology in Vitro, 2023 - Elsevier
Airway remodelling occurs in chronic respiratory diseases (CRDs) such as asthma and
chronic obstructive pulmonary disease (COPD). It is characterized by aberrant activation of …

Anti‐inflammatory and anticancer activities of Naringenin‐loaded liquid crystalline nanoparticles in vitro

R Wadhwa, KR Paudel, LH Chin… - Journal of food …, 2021 - Wiley Online Library
In this study, we had developed Naringenin‐loaded liquid crystalline nanoparticles (LCNs)
and investigated the anti‐inflammatory and anticancer activities of Naringenin‐LCNs against …