Fractal motor activity regulation and sex differences in preclinical Alzheimer's disease pathology

L Gao, P Li, A Gaba, E Musiek… - Alzheimer's & Dementia …, 2021 - Wiley Online Library
Introduction Degradation in fractal motor activity regulation (FMAR), a measure of multiscale
self‐similarity of motor control, occurs in aging and accelerates with clinical progression to …

Altered Motor Activity Patterns within 10-Minute Timescale Predict Incident Clinical Alzheimer's Disease

H Sun, P Li, L Gao, J Yang, L Yu… - Journal of …, 2024 - content.iospress.com
Background: Fractal motor activity regulation (FMAR), characterized by self-similar temporal
patterns in motor activity across timescales, is robust in healthy young humans but degrades …

[HTML][HTML] Fractal regulation and incident Alzheimer's disease in elderly individuals

P Li, L Yu, ASP Lim, AS Buchman, FAJL Scheer… - Alzheimer's & …, 2018 - Elsevier
Introduction Healthy physiological systems exhibit fractal regulation (FR), generating similar
fluctuation patterns in physiological outputs across different time scales. FR in motor activity …

[HTML][HTML] Interaction between the progression of Alzheimer's disease and fractal degradation

P Li, L Yu, J Yang, MT Lo, C Hu, AS Buchman… - Neurobiology of …, 2019 - Elsevier
Many outputs from healthy neurophysiological systems including motor activity display
nonrandom fluctuations with fractal scaling behavior as characterized by similar temporal …

Noninvasive fractal biomarker of clock neurotransmitter disturbance in humans with dementia

K Hu, DG Harper, SA Shea, EG Stopa, FAJL Scheer - Scientific reports, 2013 - nature.com
Human motor activity has a robust, intrinsic fractal structure with similar patterns from
minutes to hours. The fractal activity patterns appear to be physiologically important because …

Assessment of fractal characteristics of locomotor activity of geriatric in-patients with Alzheimer's dementia

SE Huber, P Sachse, A Mauracher… - Frontiers in Aging …, 2019 - frontiersin.org
Introduction Many physiological signals yield fractal characteristics, ie, finer details at higher
magnifications resemble details of the whole. Evidence has been accumulating that such …

Higher motor cortical excitability linked to greater cognitive dysfunction in Alzheimer's disease: results from two independent cohorts

S Zadey, SS Buss, K McDonald, DZ Press… - Neurobiology of …, 2021 - Elsevier
Prior studies have reported increased cortical excitability in people with Alzheimer's disease
(AD), but findings have been inconsistent, and how excitability relates to dementia severity …

Electroencephalographic fractal dimension in healthy ageing and Alzheimer's disease

FM Smits, C Porcaro, C Cottone, A Cancelli… - PloS one, 2016 - journals.plos.org
Brain activity is complex; a reflection of its structural and functional organization. Among
other measures of complexity, the fractal dimension is emerging as being sensitive to …

Nonlinear indices of circadian changes in individuals with dementia and aggression

LA Etcher, A Whall, R Kumar, D Devanand… - Psychiatry research, 2012 - Elsevier
Nonlinear analyses of actigraphy data were utilized to investigate circadian rest-activity
system motor control in nursing-home residents with dementia and with/without aggressive …

Brain Dynamics Complexity as a Signature of Cognitive Decline in Parkinson's Disease

E Fiorenzato, S Moaveninejad, L Weis… - Movement …, 2024 - Wiley Online Library
Background Higuchi's fractal dimension (FD) captures brain dynamics complexity and may
be a promising method to analyze resting‐state functional magnetic resonance imaging …