Emerging therapeutic biomarkers in endometrial cancer

P Dong, M Kaneuchi, Y Konno, H Watari… - BioMed research …, 2013 - Wiley Online Library
Although clinical trials of molecular therapies targeting critical biomarkers (mTOR, epidermal
growth factor receptor/epidermal growth factor receptor 2, and vascular endothelial growth …

Molecular targets and targeted therapeutics in endometrial cancer

B Weigelt, S Banerjee - Current Opinion in Oncology, 2012 - journals.lww.com
Molecular targets and targeted therapeutics in endometrial c... : Current Opinion in Oncology
Molecular targets and targeted therapeutics in endometrial cancer : Current Opinion in …

Biologic markers in endometrial cancer treatment

IB Engelsen, LA Akslen, HB Salvesen - Apmis, 2009 - Wiley Online Library
With a lifetime risk among women of 2–3%, endometrial cancer is the most common pelvic
gynecologic malignancy in industrialized countries. Approximately 75% of cases are …

Endometrial cancer: Molecular markers and management of advanced stage disease

RC Arend, BA Jones, A Martinez, P Goodfellow - Gynecologic oncology, 2018 - Elsevier
Endometrial cancer is the most prevalent gynecologic cancer in the United States. Over the
last 10 years, death rates from endometrial cancer have been rising about 1.4% per year …

Tailored therapy based on molecular characteristics in endometrial cancer

S Lee - BioMed Research International, 2021 - Wiley Online Library
Management of endometrial cancer, an adenocarcinoma of the endometrium which
occupies most uterine corpus neoplasms, including uterine sarcomas, has been more …

Novel Molecular Targets in Endometrial Cancer: Mechanisms and Perspectives for Therapy

P Soberanis Pina, S Lheureux - Biologics: Targets and Therapy, 2024 - Taylor & Francis
Endometrial cancer (EC) has a high epidemiological impact with incidence and mortality
rising worldwide. In recent years, the integration of the pathologic and molecular …

Personalized therapy in endometrial cancer: challenges and opportunities

SN Westin, RR Broaddus - Cancer biology & therapy, 2012 - Taylor & Francis
Early stage endometrial cancer is generally curable. However, progress in the treatment of
advanced and recurrent endometrial cancer has been limited. This has led to a shift from the …

Old and new perspectives in the pharmacological treatment of advanced or recurrent endometrial cancer: Hormonal therapy, chemotherapy and molecularly targeted …

A Gadducci, S Cosio, AR Genazzani - Critical reviews in oncology …, 2006 - Elsevier
Hormonal therapy and chemotherapy play a major role in the management of advanced or
recurrent endometrial cancer. Progesterone therapy obtains overall response rates ranging …

[HTML][HTML] Moving forward with actionable therapeutic targets and opportunities in endometrial cancer: NCI clinical trials planning meeting report on identifying key …

HJ MacKay, DA Levine, VL Bae-Jump, DW Bell… - Oncotarget, 2017 - ncbi.nlm.nih.gov
The incidence and mortality rates from endometrial cancer are increasing. There have been
no new drugs approved for the treatment of endometrial cancer in decades. The National …

[HTML][HTML] Endometrial cancer: molecular classification and future treatments

B Corr, C Cosgrove, D Spinosa, S Guntupalli - BMJ medicine, 2022 - ncbi.nlm.nih.gov
The treatment for endometrial cancer is rapidly evolving with the development of molecular
analysis and novel strategies. Surgical resection, cytotoxic chemotherapy, endocrine or …