[HTML][HTML] Roles of PRR-mediated signaling pathways in the regulation of oxidative stress and inflammatory diseases

P Li, M Chang - International journal of molecular sciences, 2021 - mdpi.com
Oxidative stress is a major contributor to the pathogenesis of various inflammatory diseases.
Accumulating evidence has shown that oxidative stress is characterized by the …

ROS and ROS‐mediated cellular signaling

J Zhang, X Wang, V Vikash, Q Ye, D Wu… - Oxidative medicine …, 2016 - Wiley Online Library
It has long been recognized that an increase of reactive oxygen species (ROS) can modify
the cell‐signaling proteins and have functional consequences, which successively mediate …

Reactive oxygen species: drivers of physiological and pathological processes

J Checa, JM Aran - Journal of Inflammation research, 2020 - Taylor & Francis
Abstract Since the Great Oxidation Event, about 2.4 billion years ago, the Earth is immersed
in an oxidizing atmosphere. Thus, it has been proposed that excess oxygen, originally a …

Redox regulation of inflammation: old elements, a new story

Y Lei, K Wang, L Deng, Y Chen… - Medicinal research …, 2015 - Wiley Online Library
Inflammation is an essential immune response characterized by pain, swelling, redness,
heat, and impaired function. A controlled acute inflammatory response is necessary to fight …

Linking oxidative stress to inflammation: Toll-like receptors

R Gill, A Tsung, T Billiar - Free Radical Biology and Medicine, 2010 - Elsevier
Injury caused by oxidative stress occurs in many clinical scenarios involving ischemia and
reperfusion such as organ transplantation, hemorrhagic shock (HS), myocardial infarction …

[HTML][HTML] Instrumental role for reactive oxygen species in the inflammatory response

D Fokam, D Hoskin - Frontiers in Bioscience-Landmark, 2020 - imrpress.com
Because of their highly reactive nature and potentially toxic characteristic, reactive oxygen
species (ROS) have had a bad reputation for years. However, under certain conditions, ROS …

Role and mechanism of ROS scavengers in alleviating NLRP3‐mediated inflammation

T Sho, JX Xu - Biotechnology and applied biochemistry, 2019 - Wiley Online Library
Inflammation, as a common immune response to various infections or injuries, can cause
many dangerous and complicated diseases. Inflammasome is a protein complex playing a …

Oxidative stress, consequences and ROS mediated cellular signaling in rheumatoid arthritis

AR Phull, B Nasir, I ul Haq, SJ Kim - Chemico-biological interactions, 2018 - Elsevier
There are numerous extra-and intra-cellular processes involved in the production of reactive
oxygen species (ROS). Augmented ROS generation can cause the damage of biomolecules …

[PDF][PDF] The pattern recognition receptors and lipopolysaccharides (LPS)-induced systemic inflammation

YL Hung, K Suzuki - Int. J. Res. Stud. Med. Health Sci, 2017 - ijrsmhs.com
The inflammatory response of innate immune system deals with infection of microorganism,
tissue injury and malfunction. It is triggered by pattern recognition receptors (PRRs) which …

Crosstalk between reactive oxygen species and pro-inflammatory markers in developing various chronic diseases: a review

Y Ranneh, F Ali, AM Akim, HA Hamid… - Applied Biological …, 2017 - Springer
The inflammation process in the human body plays a central role in the pathogenesis of
many chronic diseases. In addition, reactive oxygen species (ROS) exert potentially a …