The road to restoring neural circuits for the treatment of Alzheimer's disease

RG Canter, J Penney, LH Tsai - Nature, 2016 - nature.com
Alzheimer's disease is a progressive loss of memory and cognition, for which there is no
cure. Although genetic studies initially suggested a primary role for amyloid-in Alzheimer's …

Pathways towards and away from Alzheimer's disease

MP Mattson - Nature, 2004 - nature.com
Slowly but surely, Alzheimer's disease (AD) patients lose their memory and their cognitive
abilities, and even their personalities may change dramatically. These changes are due to …

Stop Alzheimer's before it starts

E McDade, RJ Bateman - Nature, 2017 - nature.com
Stop Alzheimer’s before it starts | Nature Skip to main content Thank you for visiting nature.com.
You are using a browser version with limited support for CSS. To obtain the best experience …

Alzheimer's disease

L Mucke - Nature, 2009 - nature.com
The neurodegenerative disorder Alzheimer's disease is becoming more prevalent in ageing
populations worldwide. The identification of effective treatments will require a better …

Alzheimer's disease

R Hodson - Nature, 2018 - go.gale.com
Alzheimer's disease - Document - Gale OneFile: Health and Medicine Use this link to get back
to this page. Copy Skip to Content Library Menu: Google Scholar Discovery Partner English …

Translating cell biology into therapeutic advances in Alzheimer's disease

DJ Selkoe - Nature, 1999 - nature.com
Studies of the molecular basis of Alzheimer's disease exemplify the increasingly blurred
distinction between basic and applied biomedical research. The four genes so far implicated …

The amyloid hypothesis on trial

S Makin - Nature, 2018 - go.gale.com
The amyloid hypothesis on trial - Document - Gale OneFile: Health and Medicine Use this link
to get back to this page. Copy Skip to Content Library Menu: Google Scholar Discovery Partner …

The search for better animal models of Alzheimer's disease

A King - Nature, 2018 - go.gale.com
The search for better animal models of Alzheimer's disease - Document - Gale OneFile:
Health and Medicine Use this link to get back to this page. Copy Skip to Content Library …

Adult mouse astrocytes degrade amyloid-β in vitro and in situ

T Wyss-Coray, JD Loike, TC Brionne, E Lu… - Nature medicine, 2003 - nature.com
Alzheimer disease (AD) is a progressive neurodegenerative disorder characterized by
excessive deposition of amyloid-β (Aβ) peptides in the brain. One of the earliest …

Resolving controversies on the path to Alzheimer's therapeutics

DJ Selkoe - Nature medicine, 2011 - nature.com
Alzheimer's disease constitutes a personal and societal tragedy of immense proportions.
Since 1960, research in laboratories and clinics worldwide has elucidated many features of …