Vascular remodeling is the adaptive response to various physiological and
pathophysiological alterations that are closely related to aging and vascular diseases …

Because of structural and cellular differences (ie, degrees of matrix abundance and cross-
linking, mural cell density, and adventitia), large and medium-sized vessels, in comparison …

Significance: The vascular extracellular matrix (ECM) not only provides mechanical stability
but also manipulates vascular cell behaviors, which are crucial for vascular function and …

Angiogenesis is a multistep process driven by a wide range of positive and negative
regulatory factors. Extracellular matrix (ECM) plays a crucial role in the regulation of this …

Cardiovascular disease continues to grow as a massive global health burden, with coronary
artery disease being one of its most lethal varieties. The pathogenesis of atherosclerosis …

Abnormal angiogenesis and vascular remodeling contribute to pathogenesis of a number of
disorders such as tumor, arthritis, atherosclerosis, restenosis, hypertension, and …

Extracellular matrix (ECM) within the vascular network provides both a structural and
regulatory role. The ECM is a dynamic composite of multiple proteins that form structures …

Vascular diseases are the main cause of morbidity and mortality. The vascular extracellular
matrix (ECM) is essential in mechanical support, also regulating the cellular behavior …

The extracellular matrix (ECM) is an essential component of the human body that is
responsible for the proper function of various organs. Changes in the ECM have been …

The extracellular matrix (ECM) is critical for all aspects of vascular biology. In concert with
supporting cells, endothelial cells (ECs) assemble a laminin-rich basement membrane …