Platelet integrity and function critically depend on lipid composition. However, the lipid
inventory in platelets was hitherto not quantified. Here, we examined the lipidome of murine …

Lipids are diverse families of biomolecules that perform essential structural and signaling
roles in platelets. Their formation and metabolism are tightly controlled by enzymes and …

The platelet‐lipid chapter in the story of atherothrombosis is an old one, recapitulated and
revised in many contexts. For decades several stimulating facets have been added to it, both …

The function of platelets–and thereby the balance between thrombosis and hemostasis–
critically depends on their lipid composition. At the same time, platelets are capable of …

Aims Platelets play a key role in the pathophysiology of coronary artery disease (CAD) and
patients with enhanced platelet activation are at increased risk to develop adverse …

Lipids play a central role in platelet physiology. Changes in the lipidome have already been
described for basal and activated platelets. However, quantitative lipidomic data of platelet …

Background Platelets are key players in the pathophysiology of coronary artery disease
(CAD) and platelet hyperreactivity leads to increased risk of developing adverse …

Human platelets acutely increase mitochondrial energy generation following stimulation.
Herein, a lipidomic circuit was uncovered whereby the substrates for this are exclusively …

The importance of platelets for cardiovascular disease was established as early as the 19th
century. Their therapeutic inhibition stands alongside the biggest achievements in medicine …

Platelets have been shown to be associated with pathophysiological processes beyond
thrombosis, demonstrating critical additional roles in homeostatic processes, such as …