Biologically active isoquinoline alkaloids covering 2014–2018

XF Shang, CJ Yang… - Medicinal research …, 2020 - Wiley Online Library
Isoquinoline alkaloids, an important class of N‐based heterocyclic compounds, have
attracted considerable attention from researchers worldwide since the early 19th century …

Biologically active quinoline and quinazoline alkaloids part II

XF Shang, SL Morris‐Natschke… - Medicinal research …, 2018 - Wiley Online Library
To follow‐up on our prior Part I review, this Part II review summarizes and provides updated
literature on novel quinoline and quinazoline alkaloids isolated during the period of 2009 …

Plant-based isoquinoline alkaloids: A chemical and pharmacological profile of some important leads

A Singh - 2023 - indianjournals.com
Plant-based products are a one-of-a-kind source of favoured molecules with a wide scaffold
variety and broad multi-target potential for the treatment of complicated disorders. Among …

Biologically active quinoline and quinazoline alkaloids part I

XF Shang, SL Morris‐Natschke, YQ Liu… - Medicinal research …, 2018 - Wiley Online Library
Quinoline and quinazoline alkaloids, two important classes of N‐based heterocyclic
compounds, have attracted tremendous attention from researchers worldwide since the 19th …

Quinolizidine-type alkaloids: chemodiversity, occurrence, and bioactivity

W Cely-Veloza, MJ Kato, E Coy-Barrera - ACS omega, 2023 - ACS Publications
Quinolizidine alkaloids (QAs) are nitrogen-containing compounds produced naturally as
specialized metabolites distributed in plants and animals (eg, frogs, sponges). The present …

Naturally occurring plant isoquinoline N-oxide alkaloids: their pharmacological and SAR activities

VM Dembitsky, TA Gloriozova, VV Poroikov - Phytomedicine, 2015 - Elsevier
The present review describes research on novel natural isoquinoline alkaloids and their N-
oxides isolated from different plant species. More than 200 biological active compounds …

Natural isoquinoline alkaloids: Pharmacological features and multi-target potential for complex diseases

E Plazas, DR Muñoz - Pharmacological Research, 2022 - Elsevier
Complex diseases such as neurodegenerative disorders and cancer constitute a growing
public health problem due to the rising incidence and lack in effective therapies. Since …

Medicinal chemistry perspectives of 1, 2, 3, 4-tetrahydroisoquinoline analogs–biological activities and SAR studies

BK Kumar, KVGC Sekhar, S Chander, S Kunjiappan… - RSC …, 2021 - pubs.rsc.org
Isoquinoline alkaloids are a large group of natural products in which 1, 2, 3, 4-
tetrahydroisoquinolines (THIQ) form an important class. THIQ based natural and synthetic …

Recent advances in research of natural and synthetic bioactive quinolines

PY Chung, ZX Bian, HY Pun, D Chan… - Future medicinal …, 2015 - Taylor & Francis
Many natural products that consist of quinoline core are found to be bioactive and the
versatility of quinoline and its derivatives have attracted great attention in the field of drug …

Therapeutic significance of quinolines: a patent review (2013-2015)

SMA Hussaini - Expert opinion on therapeutic patents, 2016 - Taylor & Francis
Introduction: Quinoline is a versatile bicyclic heterocyclic scaffold with immense therapeutic
potential. Some of the compounds containing quinoline nucleus are agents of choice for the …