Hypoxia is important for establishing vascularization during corpus luteum formation in cattle

R Nishimura, K Okuda - Journal of Reproduction and Development, 2010 - jstage.jst.go.jp
Hypoxia-inducible factor 1 (HIF1) has been demonstrated to have critical roles in
angiogenesis via transcriptional regulation of angiogenic factors, such as vascular …

[HTML][HTML] Expression and localization of hypoxia inducible factor-1α mRNA in the porcine ovary

U Boonyaprakob, JE Gadsby, V Hedgpeth… - Canadian Journal of …, 2005 - ncbi.nlm.nih.gov
Angiogenesis is an essential process during follicular development and corpora lutea (CL)
formation. Recent studies have shown that vascular endothelial growth factor (VEGF) is an …

Contribution of hypoxia‐inducible factor‐1α to transcriptional regulation of vascular endothelial growth factor in bovine developing luteal cells

Z Zhang, D Yin, Z Wang - Animal science journal, 2011 - Wiley Online Library
Vascular endothelial growth factor (VEGF)‐dependent angiogenesis is crucial for corpus
leteum formation and their functional maintenance in mammalian ovaries. The present study …

Activation of PI3K/mTOR signaling pathway contributes to induction of vascular endothelial growth factor by hCG in bovine developing luteal cells

Z Zhang, D Yu, D Yin, Z Wang - Animal reproduction science, 2011 - Elsevier
We recently reported that HIF-1α plays a critical role in the regulation of vascular endothelial
growth factor (VEGF) expression in the developing letual cells (LCs) and VEGF-dependent …

Progesterone induces the expression of vascular endothelial growth factor (VEGF) 120 and Flk-1, its receptor, in bovine granulosa cells

T Shimizu, A Miyamoto - Animal reproduction science, 2007 - Elsevier
Vascular endothelial growth factor (VEGF) isoforms (VEGF 120 and VEGF 164) secreted by
granulosa cells are involved in thecal angiogenesis during follicular development in the …

HCG up-regulates hypoxia inducible factor-1 alpha in luteinized granulosa cells: implications for the hormonal regulation of vascular endothelial growth factor A in the …

S van den Driesche, M Myers, E Gay… - MHR: Basic science …, 2008 - academic.oup.com
Vascular endothelial growth factor (VEGF)-dependent angiogenesis is essential for normal
luteal development. Although it is believed that hypoxia is the primary inducer of VEGF, in …

Inhibition of vascular endothelial growth factor in the primate ovary up-regulates hypoxia-inducible factor-1α in the follicle and corpus luteum

WC Duncan, S van den Driesche, HM Fraser - Endocrinology, 2008 - academic.oup.com
Vascular endothelial growth factor (VEGF)-dependent angiogenesis is crucial for follicular
growth, and corpus luteum formation and function, in the primate ovary. In the ovary VEGF …

Impact of angiogenic and innate immune systems on the corpus luteum function during its formation and maintenance in ruminants

A Miyamoto, K Shirasuna, T Shimizu, M Matsui - Reproductive biology, 2013 - Elsevier
The corpus luteum (CL) is formed from an ovulated follicle, and grows rapidly to secrete
progesterone (P4) thereby supporting implantation and maintenance of pregnancy. It is now …

Hypoxia regulates cell proliferation and steroidogenesis through protein kinase A signaling in bovine corpus luteum

YF Jiang, KH Tsui, PH Wang, CW Lin, JY Wang… - Animal reproduction …, 2011 - Elsevier
Hypoxia is an important physiological process which ensures corpus luteum (CL) formation
and development, thus playing an important role in steroidogenesis. Recent studies have …

Expression pattern of HIF 1alpha and vasohibins during follicle maturation and corpus luteum function in the bovine ovary

B Berisha, D Schams, D Rodler… - … in Domestic Animals, 2017 - Wiley Online Library
Contents The aim of this study was to characterize expression patterns of hypoxia‐inducible
factor‐1alpha (HIF 1A) and vasohibin family members (VASH 1 and VASH 2) during different …