Coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has been spreading worldwide since its outbreak in December 2019, and …

Children are less likely than adults to suffer severe symptoms when infected with severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), while influenza A H1N1 severity is …

Abstract SARS-CoV-2, the causative agent of COVID-19, has tragically burdened individuals
and institutions around the world. There are currently no approved drugs or vaccines for the …

Objectives Respiratory and intestinal tract are two primary target organs of SARS-CoV-2
infection. However, detailed characterization of the host-virus interplay in infected human …

Abstract Coronavirus disease 2019 (COVID-19) outcomes vary from asymptomatic infection
to death. This disparity may reflect different airway levels of the SARS-CoV-2 receptor …

To investigate the immune response and mechanisms associated with severe coronavirus
disease 2019 (COVID-19), we performed single-cell RNA sequencing on nasopharyngeal …

Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a global pandemic with …

The newly emerged human coronavirus, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), has caused a pandemic of respiratory illness. Current evidence suggests …

The nasal mucosa constitutes the primary entry site for respiratory viruses, including severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While the imbalanced innate …

The nasal epithelium is a plausible entry point for SARS-CoV-2, a site of pathogenesis and
transmission, and may initiate the host response to SARS-CoV-2. Antiviral interferon (IFN) …