Expression and localization of epithelial aquaporins in the adult human lung
SM Kreda, MC Gynn, DA Fenstermacher… - American journal of …, 2001 - atsjournals.org
Aquaporins (AQPs) facilitate water transport across epithelia and play an important role in
normal physiology and disease in the human airways. We used in situ hybridization and …
normal physiology and disease in the human airways. We used in situ hybridization and …
Aquaporins in complex tissues. II. Subcellular distribution in respiratory and glandular tissues of rat
S Nielsen, LS King… - American Journal of …, 1997 - journals.physiology.org
The molecular pathways for fluid transport in pulmonary, oral, and nasal tissues are still
unresolved. Here we use immunocytochemistry and immunoelectron microscopy to define …
unresolved. Here we use immunocytochemistry and immunoelectron microscopy to define …
Role of aquaporins in lung liquid physiology
AS Verkman - Respiratory physiology & neurobiology, 2007 - Elsevier
Aquaporins (AQPs) are small, integral membrane proteins that facilitate water transport
across cell membranes in response to osmotic gradients. Water transport across epithelia …
across cell membranes in response to osmotic gradients. Water transport across epithelia …
Aquaporin water channels and lung physiology
AS Verkman, MA Matthay… - American Journal of …, 2000 - journals.physiology.org
Fluid transport across epithelial and endothelial barriers occurs in the neonatal and adult
lungs. Biophysical measurements in the intact lung and cell isolates have indicated that …
lungs. Biophysical measurements in the intact lung and cell isolates have indicated that …
Aquaporin-1 water channel protein in lung: ontogeny, steroid-induced expression, and distribution in rat.
LS King, S Nielsen, P Agre - The Journal of clinical …, 1996 - Am Soc Clin Investig
At birth water is rapidly reabsorbed from the distal lung in preparation for alveolar gas
exchange. To investigate a potential role for the AQP1 water channel in development, lung …
exchange. To investigate a potential role for the AQP1 water channel in development, lung …
Lung Edema Clearance: 20 Years of Progress Invited Review: Role of aquaporin water channels in fluid transport in lung and airways
Z Borok, AS Verkman - Journal of Applied Physiology, 2002 - journals.physiology.org
Water transport across epithelial and endothelial barriers in bronchopulmonary tissues
occurs during airway hydration, alveolar fluid transport, and submucosal gland secretion …
occurs during airway hydration, alveolar fluid transport, and submucosal gland secretion …
Aquaporins in complex tissues. I. Developmental patterns in respiratory and glandular tissues of rat
LS King, S Nielsen, P Agre - American Journal of …, 1997 - journals.physiology.org
Developmental expression of aquaporin water transport proteins is not well understood in
respiratory tract or secretory glands; here we define aquaporin protein ontogeny in rat …
respiratory tract or secretory glands; here we define aquaporin protein ontogeny in rat …
[HTML][HTML] Lung fluid transport in aquaporin-5 knockout mice
T Ma, N Fukuda, Y Song, MA Matthay… - The Journal of …, 2000 - Am Soc Clin Investig
The mammalian lung expresses water channel aquaporin-1 (AQP1) in microvascular
endothelia, AQP4 in airway epithelia, and AQP5 at the apical plasma membrane in type I …
endothelia, AQP4 in airway epithelia, and AQP5 at the apical plasma membrane in type I …
Decreased pulmonary vascular permeability in aquaporin-1-null humans
LS King, S Nielsen, P Agre… - Proceedings of the …, 2002 - National Acad Sciences
The molecular determinants of water permeability in the human lung are incompletely
defined. Aquaporins (AQP) are water-specific membrane channel proteins. AQP1 is present …
defined. Aquaporins (AQP) are water-specific membrane channel proteins. AQP1 is present …
[HTML][HTML] Lung fluid transport in aquaporin-1 and aquaporin-4 knockout mice
C Bai, N Fukuda, Y Song, T Ma… - The Journal of …, 1999 - Am Soc Clin Investig
The mammalian lung expresses water channel aquaporin-1 (AQP1) in microvascular
endothelia and aquaporin-4 (AQP4) in airway epithelia. To test whether these water …
endothelia and aquaporin-4 (AQP4) in airway epithelia. To test whether these water …