Drug repurposing for COVID-19: A review and a novel strategy to identify new targets and potential drug candidates

L Rodrigues, R Bento Cunha, T Vassilevskaia… - Molecules, 2022 - mdpi.com
In December 2019, the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2), the causative agent of coronavirus disease 2019 (COVID-19) was first identified in the …

Utilizing drug repurposing against COVID-19–efficacy, limitations, and challenges

V Parvathaneni, V Gupta - Life sciences, 2020 - Elsevier
The recent outbreak of Coronavirus disease (COVID-19), first in Eastern Asia and then
essentially across the world has been declared a pandemic by the WHO. COVID-19 is …

COVID-19: molecular targets, drug repurposing and new avenues for drug discovery

MR Senger, TCS Evangelista, RF Dantas… - Memórias do Instituto …, 2020 - SciELO Brasil
Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is a highly contagious infection that may break the healthcare …

A comprehensive review of drug repurposing strategies against known drug targets of COVID-19

A Khataniar, U Pathak, S Rajkhowa, AN Jha - Covid, 2022 - mdpi.com
Drug repurposing is a more inexpensive and shorter approach than the traditional drug
discovery and development process. The concept of identifying a potent molecule from a …

Drug repurposing approach to combating coronavirus: Potential drugs and drug targets

J Xu, Y Xue, R Zhou, PY Shi, H Li… - Medicinal research …, 2021 - Wiley Online Library
In the past two decades, three highly pathogenic human coronaviruses severe acute
respiratory syndrome coronavirus (SARS‐CoV), Middle East respiratory syndrome …

Combating devastating COVID-19 by drug repurposing

AY Pawar - International Journal of Antimicrobial Agents, 2020 - Elsevier
Despite advances in drug discovery, viral infections remain a major challenge for scientists
across the globe. The recent pandemic of COVID-19 (coronavirus disease 2019), caused by …

Challenges for drug repurposing in the COVID-19 pandemic era

J Sultana, S Crisafulli, F Gabbay, E Lynn… - Frontiers in …, 2020 - frontiersin.org
The coronavirus disease (COVID-19) pandemic has affected an estimated 16 million
persons and caused 0.6 million deaths worldwide by September 2020. The pandemic has …

Effectiveness of Drug Repurposing and Natural Products Against SARS-CoV-2: A Comprehensive Review

PA Velásquez, JC Hernandez, E Galeano… - Clinical …, 2024 - Taylor & Francis
Abstract The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a
betacoronavirus responsible for the COVID-19 pandemic, causing respiratory disorders, and …

Drug repurposing for COVID-19: Approaches, challenges and promising candidates

YL Ng, CK Salim, JJH Chu - Pharmacology & therapeutics, 2021 - Elsevier
Traditional drug development and discovery has not kept pace with threats from emerging
and re-emerging diseases such as Ebola virus, MERS-CoV and more recently, SARS-CoV …

[HTML][HTML] Drug repurposing in COVID-19: a review with past, present and future

K Srivastava, MK Singh - Metabolism Open, 2021 - Elsevier
The coronavirus SARS-CoV-2 which causes the COVID-19 disease is a global public health
emergency. Coronavirus are single-stranded positive-sense RNA viruses and their genome …