Background Mesenchymal stromal cells ability to reset immune functionalities may be useful
in Crohn's disease. Aim To perform a first‐in‐human phase 1 safety clinical trial of …

Background and aim Mesenchymal stromal cells (MSCs) are pluripotent cells that have
immunosuppressive effects both in vitro and in experimental colitis. Promising results of …

Background Inflammatory bowel diseases (IBD) are chronic relapsing diseases in which pro‐
inflammatory immune cells and cytokines induce intestinal tissue damage and disability …

Background & Aims Transplantation of peripheral blood stem cells has been successful
therapy for small numbers of patients with Crohn's disease (CD), but requires prior …

Aliment Pharmacol Ther 2010; 32: 939–952 Summary Background Drugs available for the
treatment of inflammatory bowel disease fail to induce and maintain remission in a …

Objective External fistulas represent a disabling manifestation of Crohn's disease with a
difficult curability and a high relapse rate despite a large therapeutic armamentarium. Stem …

Hematopoietic stem cell transplantation and mesenchymal stromal cell therapy are currently
under investigation as novel therapies for inflammatory bowel diseases. Hematopoietic stem …

Introduction Crohn's disease (CD) is a disabling chronic enteropathy sustained by a harmful
T-cell response toward antigens of the gut microbiota in genetically susceptible subjects …

Autologous bone marrow-derived mesenchymal stromal cells (MSCs) for adoptive cell
therapy of luminal Crohn's disease (CD) are being tested in clinical trials. However, CD is …

Background aims Because of their capacity to modulate the immune response and promote
tissue repair, mesenchymal stromal cells (MSC) represent a potential novel treatment for …