[HTML][HTML] Angiotensin II regulates dendritic cells through activation of NF-κB/p65, ERK1/2 and STAT1 pathways

Y Meng, C Chen, Y Liu, C Tian, HH Li - Cellular Physiology and …, 2017 - karger.com
Background: Activation of dendritic cells (DCs) is necessary to initiate immune responses.
Angiotensin II (Ang II) has been reported to have a proinflammatory and immunomodulatory …

PPAR‐γ agonist inhibits Ang II‐induced activation of dendritic cells via the MAPK and NF‐κB pathways

Z Wei‐guo, Y Hui, L Shan, Z Yun… - Immunology and cell …, 2010 - Wiley Online Library
The renin‐angiotensin system exerts a profound regulatory effect on the functional features
of dendritic cells (DCs), thus suggesting a new target of angiotensin II (Ang II) action in the …

Angiotensin-(1–7) enhances angiotensin II induced phosphorylation of ERK1/2 in mouse bone marrow-derived dendritic cells

W Nie, H Yan, S Li, Y Zhang, F Yu, W Zhu, F Fan… - Molecular …, 2009 - Elsevier
It is well known that angiotensin-(1–7)(Ang-(1–7)) counterbalances vasoconstrictive and
proliferative functions of angiotensin II (Ang II), some of those actions are via inhibition of …

Activation and suppression of renin–angiotensin system in human dendritic cells

N Lapteva, K Ide, M Nieda, Y Ando… - Biochemical and …, 2002 - Elsevier
We previously identified the gene expression of renin–angiotensin system in human
monocyte-derived dendritic cells (DCs). This study was conducted to examine the …

Ubiquitin‐activating enzyme E1 inhibitor PYR41 attenuates angiotensin II‐induced activation of dendritic cells via the IκBa/NF‐κB and MKP1/ERK/STAT1 pathways

C Chen, Y Meng, L Wang, HX Wang, C Tian… - …, 2014 - Wiley Online Library
The activation of dendritic cells (DC s) is necessary to initiate immune responses.
Angiotensin II (A ng II) can enhance the maturation and activation of DC s, but the …

Blocking of type 1 angiotensin II receptor inhibits T-lymphocyte activation and IL-2 production

S Tawinwung, N Petpiroon, P Chanvorachote - in vivo, 2018 - iv.iiarjournals.org
Background/Aim: Novel information on the role of endogenous compounds in regulating
physiological and pathological process are of interest, as it may lead to the development of …

Impaired function of dendritic cells deficient in angiotensin II type 1 receptors

K Nahmod, C Gentilini, M Vermeulen, L Uharek… - … of Pharmacology and …, 2010 - ASPET
Dendritic cells (DC) are highly specialized antigen-presenting cells with a unique ability to
activate resting T lymphocytes and initiate primary immune responses. Angiotensin II (AII) is …

AT1 receptor-mediated angiotensin II activation and chemotaxis of T lymphocytes

JL Silva-Filho, MC Souza, M das Graças Henriques… - Molecular …, 2011 - Elsevier
Angiotensin II (Ang II), a central renin–angiotensin system (RAS) effector molecule, and its
receptors, AT1 and AT2, have been shown to be involved in the inflammatory aspects of …

Angiotensin II induces tumor necrosis factor-α expression and release from cultured human podocytes

AC Rosa, L Rattazzi, G Miglio, M Collino… - Inflammation …, 2012 - Springer
Objective High levels of both angiotensin (Ang) II and tumor necrosis factor (TNF)-α have
been implicated in the pathogenesis of glomerular injury by affecting podocytes. The aim of …

Angiotensin II–induced vascular dysfunction depends on interferon-γ–driven immune cell recruitment and mutual activation of monocytes and NK-cells

S Kossmann, M Schwenk, M Hausding… - … , and vascular biology, 2013 - Am Heart Assoc
Objective—Immune cells contribute to angiotensin II (ATII)–induced vascular dysfunction
and inflammation. Interferon-γ (IFN-γ), an inflammatory cytokine exclusively produced by …