We present a new class of inhibitors of pancreatic cholesterol esterase (CEase) based on
'priviledged'5-benzylidenerhodanine and 5-benzylidene-2, 4-thiazolidinedione structural …

In a kinetic study, the interaction of bovine pancreatic cholesterol esterase (CEase) with
fused 1, 3-oxazin-4-ones and 1, 3-thiazin-4-ones was investigated, and the compounds …

Pancreatic cholesterol esterase (CEase), which is secreted from the exocrine pancreas, is a
serine hydrolase that aids in the bile salt-dependent hydrolysis of dietary cholesteryl esters …

A series of thieno [1, 3] oxazin-4-ones and thieno [1, 3] thiazin-4-ones were synthesized and
investigated as inhibitors of the α/β hydrolases cholesterol esterase (CEase) and …

Abstract A library of forty 7, 8-benzoflavone derivatives was synthesized and evaluated for
their inhibitory potential against cholesterol esterase (CEase). Among all the synthesized …

Five flavones possessing one to four phenolic groups were fully phosphorylated efficiently
and the obtained compounds showed excellent pancreatic cholesterol esterase (CEase) …

In this study, the concept of dynamic combinatorial chemistry (DCC) was applied to explore
novel cholesterol esterase (CEase) inhibitors. In the presence of enzyme, two substrates …

Due to the importance of pancreatic cholesterol esterase (CEase) as a potential target in
atherosclerosis and for the development of hypocholesterolemic agents, there are …

Pancreatic cholesterol esterase (CEase) is a serine hydrolase involved in the hydrolysis of
variety of lipids and transport of free cholesterol. In this study, pharmacophore hypotheses …

Human pancreatic cholesterol esterase (hCEase) is one of the lipases found to involve in
the digestion of large and broad spectrum of substrates including triglycerides …