The protein Bet v 1 represents the main cause for allergic reactions to birch pollen in Europe
and North America. Structurally homologous isoforms of Bet v 1 can have different properties …

Birch pollen allergy affects more than 20% of the European allergic population. On a
molecular level, birch pollen allergy can be linked to the two dominant allergens Bet v 1 and …

Abstract In Northern America and Europe a great number of people are suffering from birch
pollen allergy and pollen related food allergies. The trigger for these immunological …

Despite a high similarity with homologous protein families, only few proteins trigger an
allergic immune response with characteristic TH2 polarization. This puzzling observation is …

The ability of pathogenesis-related proteins of family 10 to bind a broad spectrum of ligands
is considered to play a key role for their physiological and pathological functions. In …

Bet v 1 is the major birch pollen allergen. A highly efficient expression and purification
scheme for mutant forms of this protein was developed on the basis of the pET expression …

Proteolytic susceptibility during endolysosomal degradation is decisive for allergic
sensitization. In the major birch pollen allergen Bet v 1 most protease cleavage sites are …

Pathogenesis-related plant proteins of class-10 (PR-10) are essential for storage and
transport of small molecules. A prominent member of the PR-10 family, the major birch …

The major birch pollen allergen, Betv1 of Betula verrucosa is the main causative agent of
birch pollen allergy in humans. Betv1 is capable of binding several physiological ligands …

The 17 kDa protein from Betula verrucosa (White Birch) pollen, Bet v 1, is the clinically most
important birch pollen allergen causing immediate Type I IgE‐mediated allergy. The three …