Nowadays, bone diseases and defects as a result of trauma, cancers, infections and
degenerative and inflammatory conditions are increasing. Consequently, bone repair and …

Bone is a regenerative organ characterized by self-renewal ability. Indeed, it is a very
dynamic tissue subjected to continuous remodeling in order to preserve its structure and …

One of the most important ideas ever produced by the application of materials science to the
medical field is the notion of biomaterials. The nanostructured biomaterials play a crucial …

Reconstruction of the damaged bone is a striking challenge in the medical field. The bone
grafts as a current treatment is associated with inherent limitations; hence, the bone tissue …

The use of bone grafts is the standard to treat skeletal fractures, or to replace and regenerate
lost bone, as demonstrated by the large number of bone graft procedures performed …

Nowadays, there has been immense progress in developing materials to support
transplanted cells. Nevertheless, the complexity of tissues is far beyond what is found in the …

The treatment of bone defects remains one of the major challenges in modern clinical
practice. Nowadays, with the increased incidence of bone disease in an aging population …

The regenerative medicine, a new discipline that merges biological sciences and the
fundamental of engineering to develop biological substitutes, has greatly benefited from …

Nowadays, biomaterials have evolved from the inert supports or functional substitutes to the
bioactive materials able to trigger or promote the regenerative potential of tissues. The …

The usual treatment for bone defects and recalcitrant nonunions is an autogenous bone
graft. However, due to the limitations in obtaining autogenous bone grafts and the morbidity …