Half-Sandwich Iridium(III), Rhodium(III), and Ruthenium(II) Complexes Chelating Hybrid sp2-N/sp3-N Donor Ligands to Achieve Improved Anticancer Selectivity
L Guo, P Li, J Li, Y Gong, X Li, Y Liu, K Yu… - Inorganic …, 2023 - ACS Publications
The biological efficacy of half-sandwich platinum group organometallic complexes of the
formula [(η5-Cpx)/(η6-arene) M (XY) Cl] 0/+(XY= bidentate ligands; Cpx= functionalized …
formula [(η5-Cpx)/(η6-arene) M (XY) Cl] 0/+(XY= bidentate ligands; Cpx= functionalized …
Mitochondria-targeted neutral and cationic iridium (iii) anticancer complexes chelating simple hybrid sp 2-N/sp 3-N donor ligands
P Li, L Guo, J Li, Z Yang, H Fu, K Lai, H Dong… - Dalton …, 2024 - pubs.rsc.org
Most platinum group-based cyclometalated neutral and cationic anticancer complexes with
the general formula [(C^ N) 2Ir (XY)] 0/+(neutral complex: XY= bidentate anionic ligand; …
the general formula [(C^ N) 2Ir (XY)] 0/+(neutral complex: XY= bidentate anionic ligand; …
Potent Half-Sandwich 16-/18-Electron Iridium (III) and Ruthenium (II) Anticancer Complexes with Readily Available Amine–Imine Ligands
L Guo, P Li, J Li, Y Gong, X Li, T Wen, X Wu… - Inorganic …, 2023 - ACS Publications
The synthesis and biological evaluation of stable 16-electron half-sandwich complexes have
remained scarce. We herein present the different coordination modes (16-electron or 18 …
remained scarce. We herein present the different coordination modes (16-electron or 18 …
Potent half-sandwich iridium (III) and ruthenium (II) anticancer complexes containing a P^ O-chelated ligand
Q Du, L Guo, M Tian, X Ge, Y Yang, X Jian, Z Xu… - …, 2018 - ACS Publications
We herein report the synthesis, characterization, and anticancer activity of a series of iridium
(III) and ruthenium (II) half-sandwich complexes of the type [(Cpx/arene) M (P^ O) Cl] PF6 …
(III) and ruthenium (II) half-sandwich complexes of the type [(Cpx/arene) M (P^ O) Cl] PF6 …
Increasing anticancer activity with phosphine ligation in zwitterionic half-sandwich iridium (III), rhodium (III), and ruthenium (II) complexes
X Hu, L Guo, M Liu, Q Zhang, Y Gong, M Sun… - Inorganic …, 2022 - ACS Publications
The synthesis and biological assessment of neutral or cationic platinum group metal-based
anticancer complexes have been extremely studied, whereas there are few reports on the …
anticancer complexes have been extremely studied, whereas there are few reports on the …
Potent Half-Sandwich Iridium(III) Anticancer Complexes Containing C∧N-Chelated and Pyridine Ligands
Z Liu, I Romero-Canelón, A Habtemariam… - …, 2014 - ACS Publications
We report the synthesis and characterization of eight half-sandwich cyclopentadienyl IrIII
pyridine complexes of the type [(η5-Cpxph) Ir (phpy) Z] PF6, in which Cpxph= C5Me4C6H5 …
pyridine complexes of the type [(η5-Cpxph) Ir (phpy) Z] PF6, in which Cpxph= C5Me4C6H5 …
Half-sandwich iridium (III) and ruthenium (II) complexes containing P^ P-chelating ligands: A new class of potent anticancer agents with unusual redox features
JJ Li, M Tian, Z Tian, S Zhang, C Yan, C Shao… - Inorganic …, 2018 - ACS Publications
A series of half-sandwich IrIII pentamethylcyclopentadienyl and RuII arene complexes
containing P^ P-chelating ligands of the type [(Cpx/arene) M (P^ P) Cl] PF6, where M= Ir …
containing P^ P-chelating ligands of the type [(Cpx/arene) M (P^ P) Cl] PF6, where M= Ir …
Serendipitous synthesis of five-coordinated half-sandwich aminoimine iridium (iii) and ruthenium (ii) complexes and their application as potent anticancer agents
Q Du, L Guo, X Ge, L Zhao, Z Tian, X Liu… - Inorganic …, 2019 - ACS Publications
Stable five-coordinated (16-electron) half-sandwich iridium (III) and ruthenium (II) complexes
are rarely reported, and their biological evaluations have not been considered to date …
are rarely reported, and their biological evaluations have not been considered to date …
Potential anticancer agent for selective damage to mitochondria or lysosomes: Naphthalimide-modified fluorescent biomarker half-sandwich iridium (III) and ruthenium …
W Ma, S Zhang, Z Tian, Z Xu, Y Zhang, X Xia… - European journal of …, 2019 - Elsevier
In this work, five naphthalimide-modified half-sandwich iridium and ruthenium complexes
([(η 5-Cp x) Ir (NˆN) Cl] PF 6,[(η 6-p-cym) Ru (NˆN) Cl] PF 6) have been presented. The …
([(η 5-Cp x) Ir (NˆN) Cl] PF 6,[(η 6-p-cym) Ru (NˆN) Cl] PF 6) have been presented. The …
Structure-activity relationships for highly potent half-sandwich organoiridium (III) anticancer complexes with C^ N-chelated ligands
Y Yang, L Guo, X Ge, S Shi, Y Gong, Z Xu… - Journal of Inorganic …, 2019 - Elsevier
We herein report the synthesis, characterization, catalytic ability in converting coenzyme
NADH to NAD+ and anticancer activity of half-sandwich iridium (III) complexes,[(η 5-Cp …
NADH to NAD+ and anticancer activity of half-sandwich iridium (III) complexes,[(η 5-Cp …