Physiological assessment of coronary artery disease (CAD) has become one of the
cornerstones of decision making for myocardial revascularization, with a large body of …

The clinical value of fractional flow reserve and non-hyperaemic pressure ratios are well
established in determining an indication for percutaneous coronary intervention (PCI) in …

Angiographic severity of coronary artery stenosis has historically been the primary guide to
revascularization or medical management of coronary artery disease. However, physiologic …

Documentation of inducible myocardial ischaemia, related to the coronary stenosis of
interest, is of increasing importance in lesion selection for percutaneous coronary …

Symptomatic non-obstructive coronary artery disease (NOCAD) is an increasingly
recognised entity that is associated with poor cardiovascular outcomes. Nearly half of those …

Fractional flow reserve is the current invasive gold standard for assessing the ischemic
potential of an angiographically intermediate coronary stenosis. Procedural cost and time …

Coronary angiography remains far and away the most accurate morphologic assessment of
the lumen of the epicardial coronary arteries. Although non-invasive imaging is rapidly …

Nearly half of all patients with angina have non-obstructive coronary artery disease
(ANOCA); this is an umbrella term comprising heterogeneous vascular disorders, each with …

Wide attention for the appropriateness of coronary stenting in stable ischaemic heart
disease (IHD) has increased interest in coronary physiology to guide decision making. For …

Ischemic heart disease secondary to coronary vascular dysfunction causes angina and
impairs quality of life and prognosis. About one-half of patients with symptoms and signs of …