Based on theoretical considerations, experimental data with cells in vitro, animal studies in
vivo, as well as a single case pilot study with one colitis patient, a consolidated hypothesis …

Creatine, a commonly used dietary supplement, plays an important role in maintaining gut
barrier function. Given that dysregulation of the intestinal epithelial barrier is a hallmark of …

It is well established that creatine supplementation, primarily when combined with resistance
training, significantly increases measures of muscle mass and performance (primarily …

Mucosal surfaces of the lower gastrointestinal tract are subject to frequent, pronounced
fluctuations in oxygen tension, particularly during inflammation. Adaptive responses to …

Although meta-analyses have raised serious doubts about the primary therapeutic role of
enteral nutrition inCrohn's disease, detailed study of these meta-analyses indicates that, as …

The pathophysiology of inflammatory bowel diseases (IBDs) is multifactorial and involves
interactions of gut luminal content with mucosal barrier and especially immune cells …

Creatine monohydrate (CrM) supplementation appears to be relatively safe based on data
from short-term and intermediate-term human studies and results from several therapeutic …

The value of nutritional support in the prevention and treatment of malnutrition in Crohn's
disease is undisputed but its role in primary therapy continues to be debated. Controlled …

Numerous health conditions affecting the musculoskeletal, cardiopulmonary, and nervous
systems can result in physical dysfunction, impaired performance, muscle weakness, and …

Creatine supplementation has been one of the most studied and useful ergogenic nutritional
support for athletes to improve performance, strength, and muscular mass. Over time …