[HTML][HTML] Cytosolic Cadherin 4 promotes angiogenesis and metastasis in papillary thyroid cancer by suppressing the ubiquitination/degradation of β-catenin

L Wu, J Xiao, D Yi, H Ding, R Wang, Z Duan… - Journal of Translational …, 2024 - Springer
Background Although the long-term prognosis of papillary thyroid cancer (PTC) is favorable,
distant metastasis significantly compromises the prognosis and quality of life for patients with …

[HTML][HTML] Roles of Cadherin2 in Thyroid Cancer

Y Chen, C Hong, Q Zhou, Z Qin - Frontiers in Oncology, 2022 - frontiersin.org
Background The majority of drug-resistant cells in Thyroid cancer (THCA) tend to exhibit an
Epithelial mesenchymal transition (EMT) phenotype, and abnormal expression of the cell …

[HTML][HTML] Cadherin‑16 inhibits thyroid carcinoma cell proliferation and invasion

X Yang, Y Li, G Liu, W Zha, Y Liu - Oncology Letters, 2022 - spandidos-publications.com
Abstract Cadherin‑16 (CDH16), a member of the cadherin family of adhesion molecules,
serves an important role in the formation and maintenance of the thyroid follicular lumen …

Cadherin-6 promotes EMT and cancer metastasis by restraining autophagy

M Gugnoni, V Sancisi, G Gandolfi, G Manzotti… - Oncogene, 2017 - nature.com
The transdifferentiation of epithelial cells toward a mesenchymal condition (EMT) is a
complex process that allows tumor cells to migrate to ectopic sites. Cadherins are not just …

Downregulation of CDH16 in papillary thyroid cancer and its potential molecular mechanism analysed by qRT-PCR, TCGA and in silico analysis

P Li, Q Wu, Y Sun, X Pan, Y Han, B Ye… - Cancer Management …, 2019 - Taylor & Francis
Objective Thyroid cancer has the highest prevalence among the cancer types that affect the
endocrine system; however, its molecular mechanisms are not yet determined. Cadherin-16 …

Cadherin‐11 increases tumor cell proliferation and metastatic potential via Wnt pathway activation

Y Liu, P Lei, RZ Samuel, AM Kashyap… - Molecular …, 2023 - Wiley Online Library
During epithelial–mesenchymal transition (EMT) in cancer progression, tumor cells switch
cadherin profile from E‐cadherin to cadherin‐11 (CDH11), which is accompanied by …

[HTML][HTML] Loss of CDH16 expression is a strong independent predictor for lymph node metastasis in Middle Eastern papillary thyroid cancer

AK Siraj, SK Parvathareddy, M Al-Rasheed… - Scientific Reports, 2023 - nature.com
Abstract Papillary Thyroid Cancer (PTC) is the most common type of thyroid cancer. The
membrane-associated glycoprotein cadherin-16 (CDH16) plays a significant role in the …

[HTML][HTML] Cadherin 6 is a new RUNX2 target in TGF-β signalling pathway

V Sancisi, G Gandolfi, M Ragazzi, D Nicoli… - PloS one, 2013 - journals.plos.org
Modifications in adhesion molecules profile may change the way tumor cells interact with the
surrounding microenvironment. The Cadherin family is a large group of transmembrane …

[HTML][HTML] Downregulated CDH3 decreases proliferation, migration, and invasion in thyroid cancer

Y Zhou, Y Chi, A Bhandari, E Xia… - American Journal of …, 2020 - ncbi.nlm.nih.gov
Background: Placental-Cadherin (CDH3), a cell adhesion molecule, is associated with the
function of cells to bind with other cells and the extracellular matrix (ECM). CDH3 is highly …

[HTML][HTML] The interaction of CDH20 with β-catenin inhibits cervical cancer cell migration and invasion via TGF-β/smad/SNAIL mediated EMT

C Li, H Ao, G Chen, F Wang, F Li - Frontiers in Oncology, 2020 - frontiersin.org
Cancer-associated cadherin 20 (CDH20) is a novel identified cadherin that is genetically
altered in several types of human cancer, including cervical cancer. However, its …