Introduction: Quinazoline and quinazolinone scaffolds represent an important class of
biologically active nitrogen heterocyclic compounds. A variety of marketed drugs are based …

Creating effective, ecologically friendly, and commercially viable synthetic routes is crucial in
the design and synthesis of organic substances. Quinazoline, a heterocyclic compound with …

Nitrogen-rich heterocycles, particularly quinazolines and quinazolinones, represent a
unique class of diversified frameworks displaying a broad spectrum of biological functions …

Introduction: Due to the increase in knowledge about cancer pathways, there is a growing
interest in finding novel potential drugs. Quinazoline is one of the most widespread scaffolds …

Drug development has been a principal driving force in the rapid maturation of the field of
medicinal chemistry during the past several decades. During this period, the intriguing and …

The presence of N-heterocycles as an essential structural motif in a variety of biologically
active substances has stimulated the development of new strategies and technologies for …

Introduction: Quinazoline is one of the most studied moieties in medicinal chemistry due to
the wide range of biological properties such as the anticancer, antibacterial, anti …

In medicinal chemistry, one of the most significant heterocyclic compounds are quinazolines,
possessing broad range of biological properties such as anti-bacterial, anti-fungal, anti-HIV …

Quinazoline is the main six-membered heterocyclic ring system reported for their biological
activities, compounds with multiple pharmacophores, which bring together knowledge of a …

Most of the drugs and pharmacologically relevant molecules possess heterocyclic ring
structures and presence of hetero atoms or groupings divulges privileged specificities in …