Mind the mushroom: natural product biosynthetic genes and enzymes of Basidiomycota

M Gressler, NA Löhr, T Schäfer, S Lawrinowitz… - Natural product …, 2021 - pubs.rsc.org
Covering: up to September 2020 Mushroom-forming fungi of the division Basidiomycota
have traditionally been recognised as prolific producers of structurally diverse and often …

Biosynthesis of bioactive natural products from Basidiomycota

HC Lin, RT Hewage, YC Lu, YH Chooi - Organic & Biomolecular …, 2019 - pubs.rsc.org
The Basidiomycota, also called club fungi, comprise a diverse group of fungi. Basidiomycota
are strongly related to ecosystem functioning along with human life. These fungi display a …

Biocatalytic portfolio of Basidiomycota

C Schmidt-Dannert - Current opinion in chemical biology, 2016 - Elsevier
Highlights•Lifestyles and ecologies of Basidiomycota are reflected in distinct biocatalytic
activities.•Basidiomycota are masters of oxidative biocatalysis involving different types of …

Traversing the fungal terpenome

MB Quin, CM Flynn, C Schmidt-Dannert - Natural product reports, 2014 - pubs.rsc.org
Covering: 1965–2014 Fungi (Ascomycota and Basidiomycota) are prolific producers of
structurally diverse terpenoid compounds. Classes of terpenoids identified in fungi include …

Genome mining reveals the evolutionary origin and biosynthetic potential of basidiomycete polyketide synthases

G Lackner, M Misiek, J Braesel, D Hoffmeister - Fungal genetics and …, 2012 - Elsevier
Numerous polyketides are known from bacteria, plants, and fungi. However, only a few have
been isolated from basidiomycetes. Large scale genome sequencing projects now help …

Biological and chemical diversity go hand in hand: Basidiomycota as source of new pharmaceuticals and agrochemicals

B Sandargo, C Chepkirui, T Cheng… - Biotechnology …, 2019 - Elsevier
The Basidiomycota constitutes the second largest higher taxonomic group of the Fungi after
the Ascomycota and comprises over 30.000 species. Mycelial cultures of Basidiomycota …

Large-scale culture as a complementary and practical method for discovering natural products with novel skeletons

Z Hu, Y Ye, Y Zhang - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to July 2020 Fungal metabolites with diverse and novel scaffolds can be
assembled from well-known biosynthetic precursors through various mechanisms. Recent …

[PDF][PDF] Draft genome of Omphalotus olearius provides a predictive framework for sesquiterpenoid natural product biosynthesis in Basidiomycota

GT Wawrzyn, MB Quin, S Choudhary… - Chemistry & biology, 2012 - cell.com
The secondary metabolome of Basidiomycota represents a largely uncharacterized source
of pharmaceutically relevant natural products. Terpenoids are the primary class of bioactive …

Unlocking fungal cryptic natural products

YM Chiang, KH Lee, JF Sanchez… - Natural product …, 2009 - journals.sagepub.com
Recent published sequencing of fungal genomes has revealed that these microorganisms
have a surprisingly large number of secondary metabolite pathways that can serve as …

Natural products from filamentous fungi and production by heterologous expression

F Alberti, GD Foster, AM Bailey - Applied microbiology and biotechnology, 2017 - Springer
Filamentous fungi represent an incredibly rich and rather overlooked reservoir of natural
products, which often show potent bioactivity and find applications in different fields …