Application of metal coordination chemistry to explore and manipulate cell biology

KL Haas, KJ Franz - Chemical reviews, 2009 - ACS Publications
Our desire to understand how the individual molecules that make up cells organize, interact,
and communicate to form living systems has led to the burgeoning field of chemical biology …

[图书][B] Principles of bioinorganic chemistry

SJ Lippard, JM Berg - 1994 - books.google.com
As one of the most dynamic fields in contemporary science, bioinorganic chemistry lies at a
natural juncture between chemistry, biology, and medicine. This rapidly expanding field …

The inorganic side of chemical biology

SJ Lippard - Nature chemical biology, 2006 - nature.com
Bioinorganic chemistry remains a vibrant discipline at the interface of chemistry and the
biological sciences. Metal ions function in numerous metalloenzymes, are incorporated into …

Emerging opportunities to manipulate metal trafficking for therapeutic benefit

EW Hunsaker, KJ Franz - Inorganic chemistry, 2019 - ACS Publications
The indispensable requirement for metals in life processes has led to the evolution of
sophisticated mechanisms that allow organisms to maintain dynamic equilibria of these ions …

Introduction: metals in medicine

KJ Franz, N Metzler-Nolte - Chemical Reviews, 2019 - ACS Publications
In 1969, Barnett Rosenberg, Loretta Van Camp, and Thomas Krigas published a seminal
paper that described the antiproliferative activity of a very simple inorganic compound, today …

Metal complexes for therapeutic applications

J Karges, RW Stokes, SM Cohen - Trends in chemistry, 2021 - cell.com
Metal complexes have been widely used for applications in the chemical and physical
sciences due to their unique electronic and stereochemical properties. For decades the use …

Transition metal speciation in the cell: insights from the chemistry of metal ion receptors

LA Finney, TV O'Halloran - Science, 2003 - science.org
The essential transition metal ions are avidly accumulated by cells, yet they have two faces:
They are put to use as required cofactors, but they also can catalyze cytotoxic reactions …

[图书][B] Inorganic aspects of biological and organic chemistry

R Hanzlik - 2012 - books.google.com
Inorganic Aspects of Biological and Organic Chemistry investigates the inorganic aspects of
biological and organic chemistry. Topics include the inorganic chemistry of group Ia and IIa …

New approaches for medicinal applications of bioinorganic chemistry

SM Cohen - Current opinion in chemical biology, 2007 - Elsevier
Inorganic and bioinorganic chemistry have made important contributions to medical science
and human health in the past half century. Today, metal-containing imaging agents and …

The many highways for intracellular trafficking of metals

E Luk, LT Jensen, VC Culotta - JBIC Journal of Biological Inorganic …, 2003 - Springer
Metal ions such as copper and manganese represent a unique problem to living cells in that
these ions are not only essential co-factors for metalloproteins, but are also potentially toxic …