Endothelial cells transduce the frictional force from blood flow (fluid shear stress) into
biochemical signals that regulate gene expression and cell behavior via specialized …

Vascular endothelium, the cellular monolayer lining the entire cardiovascular system, is
exposed to a variety of biochemical and biomechanical stimuli. Fluid shear stresses …

Responses of vascular and lymphatic endothelial cells (ECs) to fluid shear stress (FSS) from
blood or lymphatic fluid flow govern the development, physiology, and diseases of these …

Biomechanical forces generated by blood flow play an important role in the pathogenesis of
vascular disease. For example, regions exposed to non-uniform shear stresses develop …

Endothelial cells (ECs) lining blood vessel walls respond to shear stress, a fluid mechanical
force generated by flowing blood, and the EC responses play an important role in the …

Hemodynamic shear stress, the frictional force acting on vascular endothelial cells, is crucial
for endothelial homeostasis under normal physiological conditions. When discussing blood …

Flowing blood generates a frictional force called shear stress that has major effects on
vascular function. Branches and bends of arteries are exposed to complex blood flow …

Hemodynamic forces such as fluid shear stress play an active role in many physiological
and pathophysiological processes of the cardiovascular system. Shear stress resulting from …

This review places modern research developments in vascular mechanobiology in the
context of hemodynamic phenomena in the cardiovascular system and the discrete …

As the inner lining of the vessel wall, vascular endothelial cells are poised to act as a signal
transduction interface between haemodynamic forces and the underlying vascular smooth …