EPR studies of free radicals decay and survival in gamma irradiated aminoglycoside antibiotics: sisomicin, tobramycin and paromomycin

S Wilczyński, B Pilawa, R Koprowski, Z Wróbel… - European Journal of …, 2012 - Elsevier
Radiation sterilization technology is more actively used now that any time because of its
many advantages. Gamma radiation has high penetrating power, relatively low chemical …

Free radicals properties of gamma-irradiated penicillin-derived antibiotics: piperacillin, ampicillin, and crystalline penicillin

S Wilczyński, B Pilawa, R Koprowski, Z Wróbel… - Radiation and …, 2014 - Springer
The aim of this work was to determine the concentrations and properties of free radicals in
piperacillin, ampicillin, and crystalline penicillin after gamma irradiation. The radicals were …

Electron spin resonance study of radiosterilization of antibiotics: ceftazidime

T Miyazaki, T Kaneko, T Yoshimura… - Journal of …, 1994 - Wiley Online Library
Fundamental information on radiosterilization of ceftazidime was obtained by electron spin
resonance (ESR) measurement of free radicals produced in γ‐ray‐irradiated ceftazidime at …

Electron spin resonance studies of some irradiated pharmaceuticals

M Gibella, AS Crucq, B Tilquin, P Stocker… - Radiation Physics and …, 2000 - Elsevier
Five antibiotics belonging to the cephalosporins and penicillins groups have been
irradiated: anhydrous ampicilline acid, amoxicilline acid trihydrate, cefuroxime sodium salt …

Feasibility of radiation sterilization and dosimetric features of ampicillin: an electron spin resonance study

Ş Çolak - Radiation Effects and Defects in Solids, 2016 - Taylor & Francis
In the present work, it was aimed to identify radical species produced by gamma irradiation
(3–34 kGy) of solid ampicillin, to determine its spectroscopic, dosimetric, stability and kinetic …

Radiation-induced effects on cefotaxime: ESR study

JP Basly, I Basly, M Bernard - Free radical research, 1998 - Taylor & Francis
As an alternative to heat and gas exposure sterilization, ionizing radiation is gaining interest
as sterilization process for medicinal products. Detection and dosimetry of pharmaceuticals …

Gamma radiation induced effects on metronidazole

JP Basly, JL Duroux, M Bernard - International journal of pharmaceutics, 1996 - Elsevier
The use of ionizing radiation for sterilization of pharmaceuticals is now a well established
technology. In this paper, we have studied the stability of metronidazole after irradiation …

Radiation sterilization of anthracycline antibiotics in solid state

A Kaczmarek, J Cielecka-Piontek… - The Scientific World …, 2013 - Wiley Online Library
The impact of ionizing radiation generated by a beam of electrons of 25–400 kGy on the
stability of such analogs of anthracycline antibiotics as daunorubicin (DAU), doxorubicin …

Radiosterilization dosimetry by ESR spectroscopy: application to terbutaline

JP Basly, JL Duroux, M Bernard - International journal of pharmaceutics, 1996 - Elsevier
The use of ionizing radiation for sterilization of pharmaceuticals is now a well established
technology. The purpose of the present work was to apply the electron spin resonance …

ESR identification of radiosterilized pharmaceuticals: latamoxef and ceftriaxone

JP Basly, I Longy, M Bernard - International journal of pharmaceutics, 1997 - Elsevier
As an alternative to heat and gas exposure sterilization, ionizing radiation is gaining interest
as a sterilization process for medicinal products. The aim of this work was to develop …