Effect of SGLT-2 inhibitors on body composition in patients with type 2 diabetes mellitus: A meta-analysis of randomized controlled trials

R Pan, Y Zhang, R Wang, Y Xu, H Ji, Y Zhao - PLoS One, 2022 - journals.plos.org
Objective Type 2 diabetes mellitus (T2DM) is closely related to sarcopenic obesity (SO).
Body composition measurement including body weight, body mass index, waist …

Effects of SGLT-2 inhibitors on adipose tissue distribution in patients with type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled …

X Wang, N Wu, C Sun, D Jin, H Lu - Diabetology & Metabolic Syndrome, 2023 - Springer
Abstract Objective Sodium-glucose cotransporter-2 (SGLT-2) inhibitors therapies were
reported to affect adipose tissue distribution. However, the available evidence about the …

Effect of sodium-glucose transporter 2 inhibitors on sarcopenia in patients with type 2 diabetes mellitus: A systematic review and meta-analysis

S Zhang, Z Qi, Y Wang, D Song, D Zhu - Frontiers in Endocrinology, 2023 - frontiersin.org
Objective Sarcopenia has been recognized as the third category of disabling complications
in patients with type 2 diabetes mellitus (T2DM), in addition to micro-and macrovascular …

Safety and efficiency of SGLT2 inhibitor combining with insulin in subjects with diabetes: systematic review and meta-analysis of randomized controlled trials

Y Yang, S Chen, H Pan, Y Zou, B Wang, G Wang… - Medicine, 2017 - journals.lww.com
Background: We aimed to assess the safety and efficiency of the novel sodium glucose co-
transporter 2 (SGLT2) inhibitor in combinations with insulin for type 1 and type 2 diabetes …

SGLT2 inhibitors and the clinical implications of associated weight loss in type 2 diabetes: a narrative review

A Janež, P Fioretto - Diabetes Therapy, 2021 - Springer
Introduction The obesity epidemic is closely linked to the rising prevalence of type 2
diabetes (T2D). Body weight reduction remains an important challenge in patients with T2D …

[HTML][HTML] Effect of SGLT inhibitors on weight and lipid metabolism at 24 weeks of treatment in patients with diabetes mellitus: a systematic review and network meta …

M Chen, H Wang, W Cui, H Xu, Q Zheng - Medicine, 2021 - journals.lww.com
Background: The goals of improving quality of life and increasing longevity are receiving
growing amounts of attention. Body weight and lipid metabolism are closely related to …

[PDF][PDF] Effects of SGLT2 inhibitors on weight loss in patients with type 2 diabetes mellitus.

FA Ribola, FB Cançado, JHM Schoueri… - European Review for …, 2017 - europeanreview.org
SGLT2 (sodium-glucose cotrans-porter type 2) inhibitors are a new class of drugs which
reversibly block the glucose reabsorption that occurs in the kidneys. Since their mechanisms …

The efficacy and safety of SGLT2 inhibitors for adjunctive treatment of type 1 diabetes: a systematic review and meta-analysis

J Chen, F Fan, JY Wang, Y Long, CL Gao… - Scientific reports, 2017 - nature.com
To assess the efficacy and safety of the SGLT-2 inhibitors as adjunct therapy to insulin in
T1DM, clinical trials indexed in PubMed, Cochrane Library, EMbase from inception through …

[PDF][PDF] Use of SGLT-2 inhibitors in patients with type 2 diabetes mellitus and abdominal obesity: an Asian perspective and expert recommendations

WHH Sheu, SP Chan, BJ Matawaran… - Diabetes & …, 2020 - synapse.koreamed.org
The prevalence of obesity in Asia is of epidemic proportions, with an estimated 1 billion
overweight/obese individuals in the region. The majority of patients with type 2 diabetes …

The efficacy and safety of combinations of SGLT2 inhibitors and GLP-1 receptor agonists in the treatment of type 2 diabetes or obese adults: a systematic review and …

M Guo, J Gu, F Teng, J Chen, X Ma, Q Chen, Y Pu… - Endocrine, 2020 - Springer
Purpose To evaluate the efficacy and safety of combination therapy with sodium–glucose
cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists in …