Fabrication and optimization of itraconazole-loaded zein-based nanoparticles in coated capsules as a promising colon-targeting approach pursuing opportunistic …
Abstract Itraconazole (ITZ), a broad-spectrum antifungal drug, was formulated into colon-
targeting system aiming to treat opportunistic colonic fungal infections that commonly infect …
targeting system aiming to treat opportunistic colonic fungal infections that commonly infect …
Exploiting itraconazole-loaded nanomixed micelles in coated capsules as efficient colon-targeted delivery system for improved antifungal and potential anticancer …
Chronic Inflammatory bowel diseases are usually accompanied by opportunistic colonic
fungal infections. Itraconazole (ITZ), is a highly lipophilic broad-spectrum antifungal drug that …
fungal infections. Itraconazole (ITZ), is a highly lipophilic broad-spectrum antifungal drug that …
Zein nanoparticles for controlled intestinal drug release for the treatment of gastrointestinal infections
Plant-based polymers, as nanodrug delivery systems (NDDS), offer many benefits over
synthetic ones. Optimizing the interactions of the entrapped drug within the NDDS material …
synthetic ones. Optimizing the interactions of the entrapped drug within the NDDS material …
Development of an itraconazole encapsulated polymeric nanoparticle platform for effective antifungal therapy
X Ling, Z Huang, J Wang, J Xie, M Feng… - Journal of Materials …, 2016 - pubs.rsc.org
This study is to develop a novel itraconazole-loaded nanoparticle (ITZ-NP) platform for
effective antifungal therapy. First, the monomethoxypoly (ethylene glycol)-b-poly (lactic …
effective antifungal therapy. First, the monomethoxypoly (ethylene glycol)-b-poly (lactic …
Antifungal efficacy of Itraconazole loaded PLGA-nanoparticles stabilized by vitamin-E TPGS: In vitro and ex vivo studies
Abstract Itraconazole (ITZ) loaded Poly-(D, L-lactic-co-glycolic acid, PLGA) nanoparticles
(PLGA-NPs) stabilized by D-α-Tocopherol polyethylene-glycol succinate-1000 (TPGS) were …
(PLGA-NPs) stabilized by D-α-Tocopherol polyethylene-glycol succinate-1000 (TPGS) were …
Preparation of oral core–shell zein nanoparticles to improve the bioavailability of glycyrrhizic acid for the treatment of ulcerative colitis
A Wu, C Chen, J Lu, J Sun, M Xiao, X Yue… - …, 2021 - ACS Publications
In this study, oral colon-targeted adhesion core–shell nanoparticles were designed by
applying FA-Zein as the core and using pectin as the shell to enhance the low bioavailability …
applying FA-Zein as the core and using pectin as the shell to enhance the low bioavailability …
Dual Functional Eudragit® S100/L30D-55 and PLGA Colon-Targeted Nanoparticles of Iridoid Glycoside for Improved Treatment of Induced Ulcerative Colitis
C Gao, S Yu, X Zhang, Y Dang, D Han… - International Journal …, 2021 - Taylor & Francis
Aim Iridoid glycosides (IG) as the major active fraction of Syringa oblata Lindl. has a proven
anti-inflammatory effect for ulcerative colitis (UC). However, its current commercial …
anti-inflammatory effect for ulcerative colitis (UC). However, its current commercial …
Ceftazidime/Tobramycin Co-Loaded Chitosan-Coated Zein Nanoparticles against Antibiotic-Resistant and Biofilm-Producing Pseudomonas aeruginosa and …
LAA Campos, AFS Neto, AML Scavuzzi, ACDS Lopes… - Pharmaceuticals, 2024 - mdpi.com
This study aimed to co-encapsulate ceftazidime and tobramycin in zein nanoparticles coated
with chitosan and to characterize and evaluate the antibacterial and antibiofilm activity …
with chitosan and to characterize and evaluate the antibacterial and antibiofilm activity …
Itraconazole-Loaded Poly(Lactic-Co-Glycolic) Acid Nanoparticles for Improved Antifungal Activity
NR Patel, K Damann, C Leonardi, CM Sabliov - Nanomedicine, 2010 - Taylor & Francis
Aims: Poly (lactic-co-glycolic) acid (PLGA) nanoparticles containing the hydrophobic
antifungal itraconazole (ITZ) were developed to address the need for more effective means …
antifungal itraconazole (ITZ) were developed to address the need for more effective means …
Bioaccessibility of different types of phenolic compounds co-encapsulated in alginate/chitosan-coated zein nanoparticles
J Carrasco-Sandoval, M Aranda-Bustos… - Lwt, 2021 - Elsevier
Simultaneous administration of different phenolic compounds might produce a synergistic
effect offering a greater activity against chronic non-communicable diseases. This has …
effect offering a greater activity against chronic non-communicable diseases. This has …