PPAR gamma gene–a review

C Janani, BDR Kumari - … & Metabolic Syndrome: Clinical Research & …, 2015 - Elsevier
Peroxisome proliferator-activated receptor gamma (PPARγ) has been the focus of intense
research because ligands for this receptor have emerged as potent insulin sensitizers used …

The role of peroxisome proliferator-activated receptor gamma in diabetes and obesity

FS Celi, AR Shuldiner - Current diabetes reports, 2002 - Springer
Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor, which
upon activation with various natural and synthetic ligands, stimulates the transcription of …

PPARγ AND GLUCOSE HOMEOSTASIS

F Picard, J Auwerx - Annual review of nutrition, 2002 - annualreviews.org
▪ Abstract Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor
involved in the control of metabolism. Research on PPARγ is oriented towards …

PPARγ, 10 years later

MA Lazar - Biochimie, 2005 - Elsevier
It is now over 10 years since the discovery of peroxisome proliferator activated receptor γ
(PPARγ) and its unique role in adipogenesis. The subsequent identification of PPARγ as the …

PPARγ as a metabolic regulator: insights from genomics and pharmacology

DB Savage - Expert reviews in molecular medicine, 2005 - cambridge.org
Since its identification in the early 1990s, peroxisome-proliferator-activated receptor γ
(PPARγ), a nuclear hormone receptor, has attracted tremendous scientific and clinical …

Cross‐Talk between PPARγ and Insulin Signaling and Modulation of Insulin Sensitivity

A Leonardini, L Laviola, S Perrini, A Natalicchio… - PPAR …, 2009 - Wiley Online Library
PPARγ activation in type 2 diabetic patients results in a marked improvement in insulin and
glucose parameters, resulting from an improvement of whole‐body insulin sensitivity …

Peroxisome proliferator-activated receptor γ in diabetes and metabolism

SM Rangwala, MA Lazar - Trends in pharmacological sciences, 2004 - cell.com
The peroxisome proliferator-activated receptor γ (PPAR-γ) has been the focus of intense
research during the past decade because ligands for this receptor have emerged as potent …

PPARγ and diabetes: beyond the genome and towards personalized medicine

S Cataldi, V Costa, A Ciccodicola, M Aprile - Current Diabetes Reports, 2021 - Springer
Abstract Purpose of Review Full and partial synthetic agonists targeting the transcription
factor PPARγ are contained in FDA-approved insulin-sensitizing drugs and used for the …

PPAR delta: an uncompletely known nuclear receptor

A Fredenrich, PA Grimaldi - Diabetes & metabolism, 2005 - Elsevier
Peroxisome proliferator-activated receptors (PPAR) mediate some of the transcriptional
effects of fatty acids and control many physiological functions, especially in the field of …

PPARγ-mediated insulin sensitization: the importance of fat versus muscle

U Kintscher, RE Law - American journal of physiology …, 2005 - journals.physiology.org
Peroxisome proliferator-activated receptor-γ (PPARγ) is a nuclear hormone receptor that
functions as a transcriptional regulator in a variety of tissues. PPARγ activation, eg, through …