Pneumonia and acute respiratory distress syndrome are common and important causes of
respiratory failure in the intensive care unit with a significant impact on morbidity, mortality …

Acute lung injury (ALI) affects over 10% of patients hospitalised in critical care, with acute
respiratory distress syndrome (ARDS) being the most severe form of ALI and having a …

The ability of the lung to perform gas exchange is made possible in part by the effective
relationship between the alveolar epithelium and the endothelium of the pulmonary …

Over the past 2 decades, measurement of biomarkers in both the airspaces and plasma
early in the course of acute lung injury has provided new insights into the mechanisms of …

An invited commentary in the Lancet in 1997 noted,“despite two decades of intense effort,
there is still no means of predicting reliably whether an individual patient will develop the …

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are a continuum of
lung changes arising from a wide variety of lung injuries, frequently resulting in significant …

Prompt diagnosis, intervention, and risk assessment are critical in caring for patients who
have sepsis but remain difficult with currently available methods. Biomarkers may become …

Objectives: Classification of patients with acute respiratory distress syndrome into hyper-and
hypoinflammatory subphenotypes using plasma biomarkers may facilitate more effective …

Rationale: Accurate prediction of mortality helps select patients for interventions aimed at
improving outcome. Objectives: Because chronic obstructive pulmonary disease is …

Objective: Numerous studies have focused on biomarkers for acute lung injury and acute
respiratory distress syndrome. Although several biomarkers have been identified, their …