Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

The interaction between Candida albicans and its host cells is characterized by a complex
interplay between the expression of fungal virulence factors, which results in adherence …

The polymorphic fungus Candida albicans is a member of the normal human microbiome. In
most individuals, C. albicans resides as a lifelong, harmless commensal. Under certain …

Until recently, epithelial cells have been a largely ignored component of host responses to
microbes. However, this has been largely overturned over the last decade as an ever …

Candida albicans, a commonly encountered fungal pathogen, causes diseases varying from
superficial mucosal complaints to life-threatening systemic disorders. Among the virulence …

Flexible adaptation to the host environment is a critical trait that underpins the success of
numerous microbes. The polymorphic fungus Candida albicans has evolved to persist in the …

While the fungus Candida albicans is a common colonizer of healthy humans, it is also
responsible for mucosal infections and severe invasive disease. Understanding the …

Candida albicans is both the most common fungal commensal microorganism in healthy
individuals and the major fungal pathogen causing high mortality in at-risk populations …

Candida albicans is a common commensal fungus that colonizes the oropharyngeal cavity,
gastrointestinal and vaginal tract, and healthy individuals' skin. In 50% of the population, C …

Highlights•The cell biology of Candida albicans is adapted both for life as a commensal and
as a pathogen.•C. albicans can either downregulate or upregulate virulence properties in …