This study examines the influence of intermittent exposure to cold, hypobaric hypoxia, and
their combination, in gut microbiota and their metabolites in vivo, and explores their effects …

Background Gut microbiota plays an important role in host health and is influenced by
multiple factors. Hypobaric hypoxia usually existing at high altitude conditions can adversely …

Chronic intermittent hypobaric hypoxia (CIHH) is a treatment of moderate hypoxia that
simulates high altitude interrupted by normoxia. Growing evidence shows that CIHH has …

This study was conducted to investigate the effects of high-altitude hypoxic environments on
the gut microbiota. Male Sprague-Dawley rats were randomly divided into three groups …

Acute high-altitude hypoxia can lead to intestinal damage and changes in gut microbiota.
Sustained and reliable oxygen enrichment can resist hypoxic damage at high altitude to a …

Gut microbiota bears adaptive potential to different environments, but little is known
regarding its responses to acute high-altitude exposure. This study aimed to evaluate the …

At high altitude (HA) hypobaric hypoxic environment manifested several pathophysiological
consequences of which gastrointestinal (GI) disorder are very common phenomena. To …

We utilised a ground-based microgravity hindlimb unloading (HU) mouse model to elucidate
the gut microbiota bacterial changes in mice under a simulated microgravity environment …

Introduction Intestinal microorganisms play an important role in the health of both humans
and animals, with their composition being influenced by changes in the host's environment …

Results from high altitude studies in humans and controlled animal experiments suggest that
hypoxia exposure induces alterations in gut microbiota composition, which may in turn affect …