[HTML][HTML] Plasma miR-19b and miR-183 as potential biomarkers of lung cancer

IA Zaporozhchenko, ES Morozkin, TE Skvortsova… - PLoS …, 2016 - journals.plos.org
Lung cancer is a complex disease that often manifests at the point when treatment is not
effective. Introduction of blood-based complementary diagnostics using molecular markers …

[HTML][HTML] Circulating miRNAs in serum as biomarkers for early diagnosis of non-small cell lung cancer

X Duan, S Qiao, D Li, S Li, Z Zheng, Q Wang… - Frontiers in …, 2021 - frontiersin.org
Background Non-small cell lung cancer (NSCLC) accounts for about 85% of lung cancers.
This study aimed to discover the potential miRNA biomarkers for early detection of NSCLC …

[HTML][HTML] Circulating miR-16-5p, miR-92a-3p, and miR-451a in plasma from lung cancer patients: potential application in early detection and a regulatory role in …

PP Reis, SA Drigo, RF Carvalho, RM Lopez Lapa… - Cancers, 2020 - mdpi.com
Background: Micro (mi) RNAs, potent gene expression regulators associated with
tumorigenesis, are stable, abundant circulating molecules, and detectable in plasma. Thus …

[HTML][HTML] Expression of miR-29c, miR-93, and miR-429 as potential biomarkers for detection of early stage non-small lung cancer

W Zhu, J He, D Chen, B Zhang, L Xu, H Ma, XG Liu… - PloS one, 2014 - journals.plos.org
Background Altered expression of miRNA expression contributes to human carcinogenesis.
This study was designed to detect aberrant miRNA expressions as a potential biomarker for …

[HTML][HTML] Plasma miR‑145, miR‑20a, miR‑21 and miR‑223 as novel biomarkers for screening early‑stage non‑small cell lung cancer

H Zhang, F Mao, T Shen, Q Luo, Z Ding… - Oncology …, 2017 - spandidos-publications.com
Non‑small cell lung cancer (NSCLC) is the leading cause of cancer‑related mortality in the
world. Late diagnosis is one of the most significant reasons for the high mortality rate of lung …

Circulating miRNA-21 and miRNA-23a expression signature as potential biomarkers for early detection of non-small-cell lung cancer

HF Hetta, AM Zahran, EA Shafik, RI El-Mahdy… - Microrna, 2019 - ingentaconnect.com
Background and Aim: Lung Cancer (LC) is a major cancer killer worldwide, and 5-yr survival
is extremely poor (≤ 15%), accentuating the need for more effective diagnostic and …

Identification of miRNAs as non-invasive biomarkers for early diagnosis of lung cancers

W Wang, W Li, M Ding, H Yuan, J Yang, W Meng, E Jin… - Tumor Biology, 2016 - Springer
Current clinical diagnostic methods lack the specificity in detecting lung cancer patients. The
issue is particularly critical for stage I and II patients. Considerable evidence showed …

Plasma miR-30a-5p as an early novel noninvasive diagnostic and prognostic biomarker for lung cancer

LB Liang, WJ Zhu, XM Chen, FM Luo - Future Oncology, 2019 - Taylor & Francis
Aim: Circulation miRNAs have become increasingly appreciated in the diagnosis and
prognosis of lung cancer. This study aims to identify and evaluate plasma miRNA-30a-5p as …

The MiR-17-92 gene cluster is a blood-based marker for cancer detection in non-small-cell lung cancer

C Yang, X Jia, J Zhou, Q Sun, Z Ma - The American Journal of the Medical …, 2020 - Elsevier
Background Lung cancer is one of the most malignant cancers threatening human health.
The miR-17-92 gene cluster is a highly conserved oncogene cluster encoding 6 miRNAs …

Circulating microRNA-339-5p and-21 in plasma as an early detection predictors of lung adenocarcinoma

Y Sun, H Mei, C Xu, H Tang, W Wei - Pathology-Research and Practice, 2018 - Elsevier
Background Many studies have shown that differentially expressed miRs in body fluids can
serve as biomarkers in non-invasive detection of the cancers. However, the clinical …