ABSTRACT Rationale and Objective Clonal hematopoiesis of indeterminate potential
(CHIP), defined by the age-related ontogenesis of expanded leukemogenic mutations …

Background Clonal hematopoiesis of indeterminate potential (CHIP) is an inflammatory
premalignant disorder resulting from acquired genetic mutations in hematopoietic stem cells …

Chronic kidney disease (CKD) was responsible for 1.2 million deaths globally in 2016.
Despite the large and growing burden of CKD, treatment options are limited and generally …

Clonal haematopoiesis of indeterminate potential (CHIP) is a preclinical condition wherein a
sizeable proportion of an individual's circulating blood cells are derived from a single …

We sought to determine the relationship between age-related clonal hematopoiesis (CH)
and chronic kidney disease (CKD). CH, defined as mosaic chromosome abnormalities …

Aim We aimed to analyse the association of clonal haematopoiesis of indeterminate
potential (CHIP) with incident heart failure (HF) in a European population cohort. Methods …

Introduction The disease trajectory of diabetic kidney disease (DKD) shows a high
interindividual variability not sufficiently explained by conventional risk factors. Clonal …

Age is the most important risk factor for cardiovascular disease and appears to be more than
a marker of cumulative exposure to other risk factors such as dyslipidemia and hypertension …

Background Clonal hematopoiesis of indeterminate potential (CHIP), the age-related
expansion of mutant hematopoietic stem cells, confers risk for multiple diseases of aging …

Abstract Purpose of Review This article summarizes the current knowledge about clonal
hematopoiesis of indeterminate potential (CHIP), its association with cardiovascular disease …