Context Myotonic dystrophies (DM) are dominantly inherited muscle disorders characterized
by myotonia, muscle weakness, and wasting. The reasons for sarcopenia in DMs are …

Rationale: The newly discovered myokine irisin has been proposed to affect obesity and
metabolism by promoting browning of white adipose tissue. However, clinical and functional …

Background Exercise stimulates the production of fibronectin type III domain-containing
protein 5 (FNDC5), which is cleaved to release a protein called irisin. This protein induces …

Background Charcot-Marie-Tooth (CMT) indicates a group of inherited polyneuropathies
whose clinical phenotypes primarily include progressive distal weakness and muscle …

Abstracts Purpose To clarify the association of circulating irisin with muscle, liver and bone,
and to evaluate irisin as a biomarker for sarcopenia in postmenopausal women. Methods …

Context: Irisin has been proposed to be a myokine mediating the effect of exercise on
adipocyte browning. The physiology of irisin in humans is not completely understood …

Context: Irisin is an exercise-induced novel myokine that drives brown-fat-like conversion of
white adipose tissue and has been suggested to be a promising target for the treatment of …

Background/aims Irisin is a hormone expressed in muscle, which is an exercise-induced
myokine triggering browning of white adipose tissue and increases metabolic genes …

Irisin is a newly discovered hormone produced by the muscle. This hormone is involved in
glucose metabolism, muscle strength and energy expenditure. As vitamin D is also known …

Numerous controversies surround the peptide hormone irisin. Although implicated as a
myokine promoting the browning of adipose tissue in rodents, its roles in humans remain …