Kinetic modeling and parametric imaging with dynamic PET for oncological applications: general considerations, current clinical applications, and future perspectives

A Dimitrakopoulou-Strauss, L Pan… - European journal of …, 2021 - Springer
Dynamic PET (dPET) studies have been used until now primarily within research purposes.
Although it is generally accepted that the information provided by dPET is superior to that of …

Dynamic whole-body PET parametric imaging: I. Concept, acquisition protocol optimization and clinical application

NA Karakatsanis, MA Lodge, AK Tahari… - Physics in Medicine …, 2013 - iopscience.iop.org
Static whole-body PET/CT, employing the standardized uptake value (SUV), is considered
the standard clinical approach to diagnosis and treatment response monitoring for a wide …

Dynamic whole-body PET parametric imaging: II. Task-oriented statistical estimation

NA Karakatsanis, MA Lodge, Y Zhou… - Physics in Medicine …, 2013 - iopscience.iop.org
In the context of oncology, dynamic PET imaging coupled with standard graphical linear
analysis has been previously employed to enable quantitative estimation of tracer kinetic …

Towards enhanced PET quantification in clinical oncology

H Zaidi, N Karakatsanis - The British journal of radiology, 2017 - academic.oup.com
Positron emission tomography (PET) has, since its inception, established itself as the
imaging modality of choice for the in vivo quantitative assessment of molecular targets in a …

Total-body PET multiparametric imaging of cancer using a voxelwise strategy of compartmental modeling

G Wang, L Nardo, M Parikh… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Quantitative dynamic PET with compartmental modeling has the potential to enable
multiparametric imaging and more accurate quantification than static PET imaging …

Tracer kinetic modeling in PET

M Bentourkia, H Zaidi - Pet Clinics, 2007 - Elsevier
Molecular imaging using PET provides a unique tool for noninvasively investigating the
biochemistry of living organs. The wide range of radiolabeled molecules makes it possible to …

PET parametric imaging: past, present, and future

G Wang, A Rahmim, RN Gunn - IEEE transactions on radiation …, 2020 - ieeexplore.ieee.org
Positron emission tomography (PET) is actively used in a diverse range of applications in
oncology, cardiology, and neurology. The use of PET in the clinical setting focuses on static …

Total-body quantitative parametric imaging of early kinetics of 18F-FDG

T Feng, Y Zhao, H Shi, H Li, X Zhang… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Parametric imaging has been shown to provide better quantitation physiologically than SUV
imaging in PET. With the increased sensitivity from a recently developed total-body PET …

First results on kinetic modelling and parametric imaging of dynamic 18F-FDG datasets from a long axial FOV PET scanner in oncological patients

H Sari, C Mingels, I Alberts, J Hu, D Buesser… - European journal of …, 2022 - Springer
Purpose To investigate the kinetics of 18 F-fluorodeoxyglucose (18 F-FDG) by positron
emission tomography (PET) in multiple organs and test the feasibility of total-body …

Dynamic whole-body PET imaging: principles, potentials and applications

A Rahmim, MA Lodge, NA Karakatsanis… - European journal of …, 2019 - Springer
Purpose In this article, we discuss dynamic whole-body (DWB) positron emission
tomography (PET) as an imaging tool with significant clinical potential, in relation to …