The field of prebiotic chemistry has been dedicated over decades to finding abiotic routes
towards the molecular components of life. There is nowadays a handful of prebiotically …

The challenge of a chemical approach to the origins of life problem involves comprehending
the transition from prebiotic chemistry to protobiology. This endeavor demands …

Conceiving the process of biogenesis as the evolutionary development of highly dynamic
and integrated protocell populations provides the most appropriate framework to address …

Living organisms are the most complex chemical system known to exist, yet they exploit only
a small constellation of universally conserved metabolites to support indefinite evolution …

Two recent papers reporting advances in our understanding of how a protometabolism may
have developed in a prebiotic world add new meaning to the theme “First Reactions” and …

During the last century a number of authors pointed to the inherently systemic and dynamic
nature of the living, yet their message was largely ignored by the mainstream of the scientific …

The origin of life on Earth required myriads of chemical and physical processes. These
include the formation of the planet and its geological structures, the formation of the first …

The origin-of-life problem has been traditionally conceived as the chemical challenge to find
the type of molecule and free-solution reaction dynamics that could have started Darwinian …

The origin of life is a fascinating, unresolved problem whose deciphering would have
important scientific, epistemological and social implications. Over time, philosophers and …

Protocells are supramolecular systems commonly used for numerous applications, such as
the formation of self-evolvable systems, in systems chemistry and synthetic biology. Certain …