Exogenous effects of oxytocin in five psychiatric disorders: a systematic review, meta-analyses and a personalized approach through the lens of the social salience …

L Peled-Avron, A Abu-Akel… - … & Biobehavioral Reviews, 2020 - Elsevier
Oxytocin (OT) has been implicated in various aspects of social behaviors. During the past
decades there has been a surge of interest in the therapeutic potential of OT in psychiatric …

Oxytocin effects in schizophrenia: reconciling mixed findings and moving forward

ER Bradley, JD Woolley - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Schizophrenia is a severe mental illness that causes major functional impairment. Current
pharmacologic treatments are inadequate, particularly for addressing negative and cognitive …

Oxytocin as treatment for social cognition, not there yet

AM Erdozain, O Peñagarikano - Frontiers in Psychiatry, 2020 - frontiersin.org
In a short time, oxytocin has progressed from being a regular hormone involved in parturition
and breastfeeding to be possibly the neuromodulator that has gathered the most attention …

The many faces of oxytocin: implications for psychiatry

JB Zik, DL Roberts - Psychiatry research, 2015 - Elsevier
Oxytocin is known as the 'love hormone'due its role in promoting mother–child and pair
bonding. More recent research indicates that oxytocin may have broader pro-social effects …

Potential of oxytocin in the treatment of schizophrenia

PD Shilling, D Feifel - CNS drugs, 2016 - Springer
Schizophrenia is a heterogeneous, debilitating disorder characterized by three distinct sets
of clinical features: positive symptoms, negative symptoms, and cognitive deficits. Extant …

[HTML][HTML] The role of oxytocin in social bonding, stress regulation and mental health: an update on the moderating effects of context and interindividual differences

M Olff, JL Frijling, LD Kubzansky, B Bradley… - …, 2013 - Elsevier
In this review we summarize the results and conclusions of five studies as presented in a
symposium at the 42nd annual meeting of the International Society for …

The social salience hypothesis of oxytocin

SG Shamay-Tsoory, A Abu-Akel - Biological psychiatry, 2016 - Elsevier
Oxytocin is a nonapeptide that also serves as a neuromodulator in the human central
nervous system. Over the last decade, a sizeable body of literature has examined its effects …

Do we need oxytocin to treat schizophrenia? A randomized clinical trial

J Dagani, D Sisti, M Abelli, L Di Paolo, S Pini… - Schizophrenia …, 2016 - Elsevier
Background Schizophrenia is a disabling complex mental disorder and despite all available
treatment, many patients unfortunately remain partial-or non-responders. A large body of …

Efficacy and safety of oxytocin augmentation therapy for schizophrenia: an updated systematic review and meta-analysis of randomized, placebo-controlled trials

K Oya, Y Matsuda, S Matsunaga, T Kishi… - European archives of …, 2016 - Springer
The aim of this study was to perform a systematic review and an updated and
comprehensive meta-analysis of oxytocin augmentation therapy in patients with …

A 12-week randomized controlled trial of twice-daily intranasal oxytocin for social cognitive deficits in people with schizophrenia

LF Jarskog, CA Pedersen, JL Johnson, RM Hamer… - Schizophrenia …, 2017 - Elsevier
Social cognition is impaired in people with schizophrenia and these deficits are strongly
correlated with social functioning. Oxytocin is a hypothalamic peptide that contributes to …