MicroRNA and human bone health

VKF Cheng, PCM Au, KCB Tan… - Journal of Bone and …, 2019 - academic.oup.com
The small non coding microRNAs (miRNAs) are post transcription regulators that modulate
diverse cellular process in bone cells. Because optimal miRNA targeting is essential for their …

MicroRNA variants as genetic determinants of bone mass

NS Dole, AM Delany - Bone, 2016 - Elsevier
Single nucleotide polymorphisms (SNPs) are the most abundant genetic variants that
contribute to the heritability of bone mass. MicroRNAs (miRNAs, miRs) are key post …

Global miRNA expression and correlation with mRNA levels in primary human bone cells

N Laxman, CJ Rubin, H Mallmin, O Nilsson, T Pastinen… - Rna, 2015 - rnajournal.cshlp.org
MicroRNAs (miRNAs) are important post-transcriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. The aim …

Deregulated miRNAs in bone health: Epigenetic roles in osteoporosis

D Bellavia, A De Luca, V Carina, V Costa, L Raimondi… - Bone, 2019 - Elsevier
MicroRNA (miRNA) has shown to enhance or inhibit cell proliferation, differentiation and
activity of different cell types in bone tissue. The discovery of miRNA actions and their targets …

The emerging role of microRNAs in bone remodeling and its therapeutic implications for osteoporosis

Q Feng, S Zheng, J Zheng - Bioscience reports, 2018 - portlandpress.com
Osteoporosis, a common and multifactorial disease, is influenced by genetic factors and
environments. However, the pathogenesis of osteoporosis has not been fully elucidated yet …

[HTML][HTML] SNPs in bone-related miRNAs are associated with the osteoporotic phenotype

L De-Ugarte, E Caro-Molina, M Rodríguez-Sanz… - Scientific reports, 2017 - nature.com
Biogenesis and function of microRNAs can be influenced by genetic variants in the pri-
miRNA sequences leading to phenotypic variability. This study aims to identify single …

MicroRNAs in bone diseases

L Gennari, S Bianciardi, D Merlotti - Osteoporosis International, 2017 - Springer
MicroRNAs are small, noncoding single-stranded RNAs that have emerged as important
posttranscriptional regulators of gene expression, with an essential role in vertebrate …

MicroRNA functions in osteogenesis and dysfunctions in osteoporosis

AJ Van Wijnen, J Van De Peppel… - Current osteoporosis …, 2013 - Springer
MicroRNAs (miRNAs) are critical post-transcriptional regulators of gene expression that
control osteoblast mediated bone formation and osteoclast-related bone remodeling …

[HTML][HTML] MicroRNAs and post-transcriptional regulation of skeletal development

B Gámez, E Rodriguez-Carballo… - Journal of molecular …, 2014 - jme.bioscientifica.com
MicroRNAs (miRNAs) have become integral nodes of post-transcriptional control of genes
that confer cellular identity and regulate differentiation. Cell-specific signaling and …

Regulation of bone metabolism by microRNAs

H Taipaleenmäki - Current osteoporosis reports, 2018 - Springer
Abstract Purpose of Review The small non-coding microRNAs (miRNAs) have emerged as
important post-transcriptional regulators of various physiological and pathological …